Micro
ProblemIn mammals, implantation involves interactions between an activated blastocyst and a receptive endometrium. There are controversies on the role of microRNAs in preimplantation embryo development. The actions of endometrial microRNAs on implantation are beginning to be understood.Method of StudyReview of literature on microRNAs in preimplantation
Weimin Liu +5 more
openalex +5 more sources
RO8191, a new compound for initiating embryo implantation in mice [PDF]
During early pregnancy in mice, leukemia inhibitory factor (LIF) regulates embryo implantation by activating the JAK/STAT3 signaling pathway. The STAT3 pathway has been recognized to play a critical role in embryo implantation; however, it remains ...
Junlan Shu +8 more
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Role of circadian clock in female embryo implantation [PDF]
Accumulating evidence indicates that circadian rhythm disruption can exert an impact on female reproductive function. In the context of female reproduction, the success of embryo implantation is of utmost significance as it is an essential process for ...
Yukai Zhou +12 more
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ABSTRACT Embryo implantation in humans is interstitial, meaning the entire conceptus embeds in the endometrium before the placental trophoblast invades beyond the uterine mucosa into the underlying inner myometrium. Once implanted, embryo survival pivots on the transformation of the endometrium into an anti-inflammatory placental bed ...
Muter J, Lynch VJ, McCoy RC, Brosens JJ.
europepmc +3 more sources
Role of adipokines in embryo implantation [PDF]
Embryo implantation is a complex process in which multiple molecules acting together under strict regulation. Studies showed the production of various adipokines and their receptors in the embryo and uterus, where they can influen ce the maternal-fetal ...
Davoud Jafari-Gharabaghlou +10 more
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Role of microRNAs in embryo implantation [PDF]
Failure of embryo implantation is a major limiting factor in early pregnancy and assisted reproduction. Determinants of implantation include the embryo viability, the endometrial receptivity, and embryo-maternal interactions.
Jingjie Liang +2 more
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Analysis of factors related to embryo implantation/clinical pregnancy in patients with severe Intrauterine Adhesions(IUA) undergoing In Vitro Fertilization-Embryo Transfer (IVF-ET) following hysteroscopic adhesiolysis: a retrospective study [PDF]
Purpose To investigate factors influencing embryo implantation and clinical pregnancy in patients with severe IUA undergoing IVF-ET and to develop a predictive model.
Jiao Lin +10 more
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Modeling embryo-endometrial interface recapitulating human embryo implantation. [PDF]
The initiation of human pregnancy is marked by the implantation of an embryo into the uterine environment; however, the underlying mechanisms remain largely elusive. To address this knowledge gap, we developed hormone-responsive endometrial organoids (EMO), termed apical-out (AO)–EMO, which emulate the in vivo architecture of endometrial tissue. The AO-
Shibata S +18 more
europepmc +3 more sources
A pilot study of cervicovaginal microbiome patterns associated with embryo implantation outcomes in endometriosis-associated infertility. [PDF]
Li Y +6 more
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Cell-cycle machinery is critical in regulating uterine steroid hormone for embryo implantation and development [PDF]
Proper embryo implantation is necessary for a successful pregnancy. In this issue of the JCI, Aljubran et al. identified the cell cycle regulatory protein cyclin A2 (CCNA2) as a factor in supporting embryo implantation and embryo development. Endometrial
Francesco J. DeMayo
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