Results 1 to 10 of about 4,847 (109)
Embryo implantation and GnRH antagonists [PDF]
Human Reproduction, 2000 When gonadotrophin-releasing hormone (GnRH) was discovered, the agonist and antagonist of GnRH were developed to control the release of FSH and LH by the gonadotrophs. More than 10 years of research were needed to develop a GnRH antagonist free of histamine release.
Bernadette Mannaerts, K. Gordon
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Developmental Biology, 2000 A lesson learned from modern developmental biology is the striking degree of conservation of strategies and molecules used to program developmental events in species as diverse as insects, birds, amphibians, and mammals. Nonetheless, mammals retain distinctions with regard to the strategies used to protect and nourish their offspring during development,
Carson, Daniel D. +6 more
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Role of adipokines in embryo implantation [PDF]
Endocrine Connections, 2021 Embryo implantation is a complex process in which multiple molecules acting together under strict regulation. Studies showed the production of various adipokines and their receptors in the embryo and uterus, where they can influence the maternal-fetal transmission of metabolites and embryo implantation.
Mostafa Vaghari-Tabari +11 more
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Development, 2023 ABSTRACT Embryo implantation in humans is interstitial, meaning the entire conceptus embeds in the endometrium before the placental trophoblast invades beyond the uterine mucosa into the underlying inner myometrium. Once implanted, embryo survival pivots on the transformation of the endometrium into an anti-inflammatory placental bed ...
Joanne Muter +3 more
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Role of microRNAs in embryo implantation [PDF]
Reproductive Biology and Endocrinology, 2017 Failure of embryo implantation is a major limiting factor in early pregnancy and assisted reproduction. Determinants of implantation include the embryo viability, the endometrial receptivity, and embryo-maternal interactions. Multiple molecules are involved in the regulation of implantation, but their specific regulatory mechanisms remain unclear ...
Jingjie Liang +2 more
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Microbead Implantation in the Zebrafish Embryo [PDF]
Journal of Visualized Experiments, 2015 The zebrafish has emerged as a valuable genetic model system for the study of developmental biology and disease. Zebrafish share a high degree of genomic conservation, as well as similarities in cellular, molecular, and physiological processes, with other vertebrates including humans.
Rebecca A. Wingert +2 more
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The evolution of embryo implantation
The International Journal of Developmental Biology, 2014 Embryo implantation varies widely in placental mammals. We review this variation in mammals with a special focus on two features: the depth of implantation and embryonic diapause. We discuss the two major types of implantation depth, superficial and interstitial, and map this character on a well-resolved molecular phylogenetic tree of placental mammals.
Derek E. Wildman +5 more
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The Role of Extracellular Vesicles in Embryo Implantation [PDF]
Frontiers in Endocrinology, 2022 Extracellular vesicles (EVs) are membrane-coating nanoparticles derived from cells. The effect of cell-to-cell communication mediated by EVs has been investigated in different fields of physio-logical as well as pathological process in recent years. Reproduction, regarded as a definitive characteristic of organisms, has been a focus in both animal and ...
Kaiyu Chen +5 more
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Implantation potential of mosaic embryos [PDF]
Systems Biology in Reproductive Medicine, 2017 Chromosomal mosaicism is a relatively common finding in human IVF embryos. However, the association between mosaicism in trophoectoderm and inner mass cells, the mechanisms involved, and its effects on implantation are far from established. We retrospectively reanalyzed array-CGH results from 1,362 trophoectoderm biopsies.
Joaquín Llácer +6 more
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Evolutionary divergence of embryo implantation in primates
Philosophical Transactions of the Royal Society B: Biological Sciences, 2022 Implantation of the conceptus into the uterus is absolutely essential for successful embryo development. In humans, our understanding of this process has remained rudimentary owing to the inaccessibility of early implantation stages. Non-human primates recapitulate many aspects of human embryo development and provide crucial insights into trophoblast ...
Siriwardena, Dylan, Boroviak, Thorsten E
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