Results 141 to 150 of about 108,223 (347)
Glioblastoma (GBM) is the most aggressive primary brain tumor, with glioma stem cells (GSCs) driving treatment resistance. This study reveals that lactate promotes histone lactylation (H3K18la) at the VRK1 promoter, regulating GSC stemness and proliferation via the H3K18la/VRK1/YBX1/SOX2 pathway. The VRK1‐targeted nanoliposome A/TMZ‐siVRK1 demonstrates
Jinna Li +4 more
wiley +1 more source
Neural tube-ectoderm interactions are required for trigeminal placode formation [PDF]
Cranial sensory ganglia in vertebrates develop from the ectodermal placodes, the neural crest, or both. Although much is known about the neural crest contribution to cranial ganglia, relatively little is known about how placode cells form, invaginate and
Bronner-Fraser, Marianne +3 more
core
SEQUELAE OF THE LD/50 X-RAY EXPOSURE OF THE PRE-IMPLANTATION MOUSE EMBRYO: DAYS 0.0 TO 5.0
Roberts Rugh +6 more
openalex +2 more sources
Similar pregnancy and implantation rates after transfer of frozen-thawed embryos from ICSI and standard IVF [PDF]
Kersti Lundin +3 more
openalex +1 more source
This study establishes pharmacological microglial inhibition as a therapeutic strategy, demonstrating its capacity to remodel the lesion microenvironment through significant reduction of extracellular matrix deposition. This permissive environmental transformation facilitates robust regeneration of the reticulospinal tract, and reconstructs functional ...
Run Li +11 more
wiley +1 more source
Isoform-Specific Expression of Neuregulin Family Members in the Mouse Uterus During Embryo Implantation 299 [PDF]
Jeff Reese, Naoko Brown, Sudhansu K. Dey
openalex +1 more source
Repeated neonatal sevoflurane exposure impairs adolescent fear memory through Igfbp2 downregulation in paraventricular thalamus‐central amygdala glutamatergic projections. Restoring Igfbp2 or activating this circuit rescues memory deficits, neuronal excitability, and spine density, identifying a precise molecular target for preventing anesthesia ...
Weiming Zhao +16 more
wiley +1 more source
P-217. The cleavage rate of the embryos affects the pregnancy and implantation rates [PDF]
Kersti Lundin, Brita Söderlund
openalex +1 more source
Schematic illustration of resident macrophages in Immune checkpoint inhibitor‐associated nephrotoxicity (ICI‐AN). Using an integrated approach (including imaging mass cytometry, transcriptomics, and murine models), this study reveals that resident macrophages drive immune‐stromal interactions in ICI‐AN, promoting fibroblast activation through CXCL9 and
Yanhong Ma +11 more
wiley +1 more source
Blastocyst-endometrium interaction: intertwining a cytokine network
The successful implantation of the blastocyst depends on adequate interactions between the embryo and the uterus. The development of the embryo begins with the fertilized ovum, a single totipotent cell which undergoes mitosis and gives rise to a ...
W.A. Castro-Rendón +3 more
doaj

