Results 161 to 170 of about 62,103 (297)

Embryo-uterine interaction coordinates mouse embryogenesis during implantation

Embryo implantation into the uterus marks a key transition in mammalian development. In mice, implantation is mediated by the trophoblast and is accompanied by a morphological transition from the blastocyst to the egg cylinder.
Belousov, Roman, Blotenburg, Marloes, Kreshuk, Anna, Kromm, Dimitri, Erzberger, Anna, Zeller, Peter, Uhlmann, Virginie, Ellenberg, Jan, van Oudenaarden, Alexander, Hugger, Johannes, Hiiragi, Takashi, 柊, 卓志, Hufnagel, Lars, Rezakhani, Saba, Lutolf, Matthias P, Wolny, Adrian, Nikolaev, Mikhail, Bondarenko, Vladyslav   +17 more
core   +1 more source

Comparative analysis of the transcriptome and methylome in distinct trophoblast populations at the time of embryo implantation in mares. [PDF]

BMC Genomics
Jaworska J, Tobolski D, Salem SE, Ropka-Molik K, Ząbek T, Szmatoła T, Kahler A, Wocławek-Potocka I, Piórkowska K, de Mestre AM.   +9 more
europepmc   +1 more source

Bridging maternal effects and epitranscriptomics: A novel perspective in developmental biology

Developmental Dynamics, EarlyView.
Abstract Maternal effects, encompassing both genetic (maternally expressed gene products) and non‐genetic (maternal state) influences, are powerful determinants of offspring phenotype, yet their RNA‐level mechanisms remain incompletely resolved. In parallel, epitranscriptomics, an emerging field centered on chemical modifications to RNA, has revealed ...
Ehsan Pashay Ahi
wiley   +1 more source

Efficacy of glucocorticoids treatment in recurrent embryo implantation failure. [PDF]

Cell Death Discov
Cai QY, Tang WZ, Li ZM, Li JZ, Zhi XQ, Yang QH, Sheng J, Liu TH.   +7 more
europepmc   +1 more source

Oogenesis and germinal bed morphology of the brown anole (A. sagrei)

Developmental Dynamics, EarlyView.
Abstract Background The brown anole is a model species of the genus Anolis, a squamate (encompassing lizards and snakes) group widely studied in evolutionary, behavioral, and developmental biology. Full genome annotation, the establishment of gene editing techniques, and comprehensive description of reproductive tract morphology and embryogenesis in ...
Bonnie K. Kircher, Antonia Weberling, Erin J. Vance, Natalia A. Shylo, Katherine Starr, Zoe B. Griffin, Hannah Wilson, Melainia McClain, Florian Hollfelder, Suzannah A. Williams, Thomas J. Sanger, Richard R. Behringer, Paul A. Trainor   +12 more
wiley   +1 more source

Correction: Different responses of luminal and glandular epithelium during mouse embryo implantation. [PDF]

Front Vet Sci
Cui W, Guan X, Liu P, Xu QX, Xie J, Jiao Y, Jin L, Wang PC, Yang Z.   +8 more
europepmc   +1 more source

Targeted senotherapy improves electrographic and behavioral outcomes in a mouse model of temporal lobe epilepsy

Epilepsia, EarlyView.
Abstract Objective Current pharmacotherapy for temporal lobe epilepsy (TLE) is limited to symptomatic treatment and leaves approximately one third of patients with inadequate seizure control. Discovering disease‐modifying targets is an unmet clinical need. We have previously identified senescent cells (SCs) as one such target. Many drugs that eliminate
David J. McFall, Abbas I. Hussain, Michelle Cho, Patrick A. Forcelli   +3 more
wiley   +1 more source

Linking the Warburg effect to endometrial receptivity: metabolic parallels in embryo implantation. [PDF]

Front Cell Dev Biol
Zhang X, Zhu Q, Nie W, Yan X, Yuan Z, Tian L.   +5 more
europepmc   +1 more source

CaMKIIβ insufficiency disrupts cortical networks, producing aberrant low‐gamma oscillations and seizure susceptibility

Epilepsia, EarlyView.
Abstract Objective Pathogenic variants in the calcium/calmodulin‐dependent protein kinase II B gene (CAMK2B) have been associated with neurodevelopmental disorders, including epilepsy, yet the mechanisms underlying cortical dysfunction remain largely unclear.
Hiroki Mutoh, Kazushi Aoto, Atsuo Fukuda, Hirotomo Saitsu   +3 more
wiley   +1 more source

The role of microRNAs in the pre-implantation mammalian embryo [PDF]

MicroRNAs (miRNAs) are small non-coding RNA molecules that exert regulatory actions in gene expression acting mainly via RNA silencing and post-transcriptional changes.
Makri, K.D.
core