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Research progress on non-invasive testing of endometrial receptivity [PDF]

open access: yesFrontiers in Reproductive Health
Endometrial receptivity plays a crucial role in the process of embryo implantation and is a key factor affecting the success rate of assisted reproductive technology. Traditional ultrasound assessment of endometrial receptivity has poor accuracy.
Lvhua Lin   +3 more
doaj   +2 more sources

Electroacupuncture may improve endometrial receptivity in controlled ovarian hyperstimulation mice by activating AVP neurons [PDF]

open access: yesFrontiers in Endocrinology
BackgroundControlled ovarian hyperstimulation (COH) can lead to reduced endometrial receptivity during the window of implantation (WOI) and disrupted expression of endometrial clock genes.
Tiantian Ma   +14 more
doaj   +2 more sources

Advances in the Study of Endometrial Receptivity and Glucose Metabolism Mechanisms in Insulin Resistance [PDF]

open access: yesEndocrinology, Diabetes & Metabolism
Introduction Insulin resistance (IR) is one of the important pathologic bases of polycystic ovary syndrome (PCOS) and an important factor contributing to infertility.
Si‐yan Huang   +7 more
doaj   +2 more sources

Using organoids to investigate human endometrial receptivity

open access: yesFrontiers in Endocrinology, 2023
The human endometrium is only receptive to an implanting blastocyst in the mid-secretory phase of each menstrual cycle. Such time-dependent alterations in function require intricate interplay of various factors, largely coordinated by estrogen and ...
Eva Dimitriadis
exaly   +3 more sources

ENTPD3 as a novel regulator of endometrial receptivity: suppressing EMT via the ATP–P2Y2 axis in patients with recurrent implantation failure [PDF]

open access: yesCellular & Molecular Biology Letters
Background Recurrent implantation failure (RIF) remains a major challenge in assisted reproductive technology and is primarily attributed to impaired endometrial receptivity. Despite its clinical significance, the precise mechanisms underlying RIF remain
Dan Mo   +12 more
doaj   +2 more sources

The mechanism study of targeting DPP4 in regulating ferroptosis and its influence on endometrial receptivity in PCOS [PDF]

open access: yesBiology of Sex Differences
Background Polycystic ovary syndrome (PCOS) impairs endometrial receptivity, contributing to reproductive dysfunction. Our previous work identified ferroptosis-related dipeptidyl Peptidase 4 (DPP4) as a key regulator of endometrial receptivity in PCOS ...
Jian Zhang   +9 more
doaj   +2 more sources

IGFBP5 Restores Endometrial Receptivity and Rescues Implantation Failure in Polycystic Ovary Syndrome [PDF]

open access: yesAdvanced Science
Polycystic ovary syndrome (PCOS) is a metabolic disorder and a major cause of infertility, affecting approximately 5–18% of women of reproductive age worldwide.
Baoying Liao   +13 more
doaj   +2 more sources

Decrypting spatiotemporal code of human endometrial receptivity [PDF]

open access: yesNature Communications
The mechanism underlying the establishment of human endometrial receptivity remains elusive, constituting a significant obstacle to advancing our knowledge of female infertility.
Yang Liu   +17 more
doaj   +2 more sources

Microengineered patient-derived endometrium-on-a-chip for the evaluation of endometrial receptivity and personalised translational medicine [PDF]

open access: yesNature Communications
Endometrial receptivity is a critical determinant of embryo implantation and early pregnancy success; however, current methods for assessing endometrial receptivity remain poorly validated and insufficiently reliable for clinical application.
Gaeun Lee   +11 more
doaj   +2 more sources

Ovarian stimulation and endometrial receptivity [PDF]

open access: yesHuman Reproduction, 1999
Endometrial receptivity is a limiting step in the success of in-vitro fertilization (IVF). To investigate this issue, we selected a specific population of high responder patients in whom implantation was impaired, even when good quality embryos were transferred.
Diana Valbuena   +2 more
exaly   +3 more sources

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