Endometrial dysfunction in embryo implantation: from molecular mechanisms to clinical management. [PDF]
Shi C +5 more
europepmc +1 more source
Structural Control of Stromal‐Immune Coupling by COL24A1 Underlies Pregnancy Maintenance
COL24A1 emerges as a collagen‐associated regulator of maternal‐fetal interface homeostasis. Its deficiency promotes a maladaptive TIMP1‐high stromal state, impaired ECM turnover, collagen accumulation, and stromal–immune dysregulation, contributing to pregnancy loss.
Teng Wu +12 more
wiley +1 more source
Proper embryo implantation is necessary for a successful pregnancy. In this issue of the JCI, Aljubran et al. identified the cell cycle regulatory protein cyclin A2 (CCNA2) as a factor in supporting embryo implantation and embryo development. Endometrial
Francesco J. DeMayo
doaj +1 more source
Electroacupuncture ameliorates embryo implantation dysfunction in mice via miR-30c-5p. [PDF]
Song JY, Dong FY.
europepmc +1 more source
SEC Mediates m6A Deposition and Transcription Pause Release to Drive Cell Identity Transition
The SEC promotes cell identity transitions by facilitating transcription pause release at key identity‐associated genes, including Klf4 and Myc during iPSC reprogramming and Nes and Tubb3 during ESC‐to‐neuroectodermal differentiation. During early iPSC reprogramming, this function additionally involves cooperation with METTL3‐associated m6A regulation.
Zhijing Zhang +9 more
wiley +1 more source
Paternal age and sperm DNA fragmentation independently affect embryonic ploidy but not euploid embryo implantation potential. [PDF]
Li Z +10 more
europepmc +1 more source
Porphyrin‐Based Porous Materials for Antibacterial Applications
Porphyrin‐based porous materials have excellent photophysical properties and tunable structures for high‐efficiency antibacterial therapy. This review comprehensively discusses the structural design strategies and synthetic pathways of the four main types of porphyrin‐based porous materials, summarizes their cross‐domain antimicrobial applications, and
Xiao‐Xue Liang +4 more
wiley +1 more source
FTO Controls Endometrial Receptivity and Embryo Implantation through Regulating m<sup>6</sup>A and H3K27me3. [PDF]
Zhang M +9 more
europepmc +1 more source
Targeted Mechanogenetics to Modulate Specific Deep Neural Circuits
This study introduces mechanogenetics, a nanobubble‐enhanced sonogenetic strategy for selective modulation of feeding‐related neural circuits in the mouse lateral hypothalamus. Mechanogenetic stimulation modulates feeding behavior through glutamatergic projections from the lateral hypothalamus to the ventral tegmental area, highlighting its potential ...
Xuandi Hou +3 more
wiley +1 more source
Correction: Maternal intestinal L. vaginalis facilitates embryo implantation and survival through enhancing uterine receptivity in sows. [PDF]
Ye Q +9 more
europepmc +1 more source

