Optimizing embryo culture conditions and spent culture media analysis as predictors of embryo quality and pregnancy [PDF]
Philosophiae Doctor - PhDThe aim of this thesis is first, to evaluate various culture conditions to improve embryo development, and secondly, to analyze spent culture media for any biomarkers that may be predictive of embryo health.
Kaskar, Khalied
core
Predicting embryo quality: mRNA expression and the preimplantation embryo
To overcome the low implantation rate (10-20%) following IVF in humans, more than two embryos are commonly replaced, potentially leading to high order multiple pregnancies with associated significantly elevated risks. Selecting the most viable embryos and transferring fewer of them could reduce this risk.
Deirdre, Corcoran +2 more
openaire +2 more sources
Introduction. Infertility, i.e. the inability to achieve a clinical pregnancy within 12 months of a regular sexual life without contraception, is a current medical problem and affects up to 15-25% of married couples in Western countries.Objective.
A. G. Syrkasheva, N. V. Dolgushina
doaj +1 more source
In vitro embryo production in agricultural animals: morphokinetic profiling as a tool to investigate embryo viability [PDF]
In response to a growing population and increasing demand for meat and dairy, the in vitro production (IVP) of embryos in agricultural animals is of vital importance to improving efficiency for breeding companies.
Hillyear, L.
core
ObjectiveThe single-embryo transfer (SET) is the recommended approach to improve the live birth rate and reduce the complications related with multiple pregnancies.
Qianqian Zhu +5 more
doaj +1 more source
The importance of cytoplasmic strings during early human embryonic development
Objectives: During human in vitro fertilisation (IVF) treatments, embryologists attempt to select the most viable embryos for embryo transfer (ET). Previously, embryos were evaluated based on light microscopic morphological parameters.
Kata Joo +6 more
doaj +1 more source
Epigenetics, embryo quality and developmental potential [PDF]
It is very important for embryologists to understand how parental inherited genomes are reprogrammed after fertilisation in order to obtain good-quality embryos that will sustain further development. In mammals, it is now well established that important epigenetic modifications occur after fertilisation.
openaire +5 more sources
Association between Number of Formed Embryos, Embryo Morphology and Clinical Pregnancy Rate after Intracytoplasmic Sperm Injection [PDF]
Introduction Infertility has a high prevalence in the general population, affecting 5 to 15% of couples in reproductive age. The assisted reproduction techniques ( ART ) include in vitro manipulation of gametes and embryos and are an important treatment
Caroline Mantovani da Luz +5 more
doaj +2 more sources
Micro-magnetic resonance imaging study of live quail embryos during embryonic development [PDF]
Eggs containing live Japanese quail embryos were imaged using micro-magnetic resonance imaging (μMRI) at 24-h intervals from Day 0 to 8, the period during which the main body axis is being laid down and organogenesis is taking place.
Welten, Monique +14 more
core +1 more source
Fertilization signatures as biomarkers of embryo quality
Abstract Fertilization underpins the vital transition from gametic meiosis to embryonic mitosis. For decades, in human IVF, microscopic observation at a single time point has limited our appreciation of the morphokinetic complexity of this process. More recently, the introduction of time lapse technology—also enhanced by combination with
Giovanni Coticchio +4 more
openaire +2 more sources

