Results 71 to 80 of about 117,827 (298)

Concentration of stromal cell‐derived factor‐1 (SDF‐1/CXCL12) in the follicular fluid is associated with blastocyst development

Reproductive Medicine and Biology, 2019
Purpose To study the association between stromal cell‐derived factor‐1 (SDF‐1/CXCL12) and vascular endothelial growth factor (VEGF) concentrations in individual human ovarian follicles and IVF outcomes.
Akemi Nishigaki, Tomoko Tsuzuki‐Nakao, Takeharu Kido, Naoko Kida, Maiko Kakita‐Kobayashi, Hiromi Murata, Hidetaka Okada   +6 more
doaj   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Prior COVID-19 infection increases degenerated oocytes but does not affect IVF outcomes: a prospective cohort study

Frontiers in Endocrinology
BackgroundThe global health crisis of coronavirus disease 2019 (COVID-19) continues to impact people of all age groups worldwide. Recent studies increasingly support that COVID-19 infection may affect reproductive function, causing subfertility and ...
Huijun Chen, Huijun Chen, Huijun Chen, Hongxin Guo, Qi Zhao, Yuan Li, Yuan Li, Ge Lin, Ge Lin, Philipp Kalk, Philipp Kalk, Berthold Hocher, Berthold Hocher, Berthold Hocher, Berthold Hocher, Fei Gong, Fei Gong   +16 more
doaj   +1 more source

Relationship between embryo quality and aneuploidies

Reproductive BioMedicine Online, 2006
Many high-grade embryos selected for transfer according to their morphological evaluation were detected to have chromosomal abnormalities after aneuploidy screening for infertility by preimplantation genetic diagnosis (PGD). The aim of this study was to detect if there is any correlation between embryo quality and genetic status. The chromosomal status
V, Baltaci, H, Satiroglu, C, Kabukçu, E, Unsal, B, Aydinuraz, O, Uner, Y, Aktas, E, Cetinkaya, F, Turhan, A, Aktan   +9 more
openaire   +2 more sources

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source

183 EXERCISE INFLUENCES EMBRYO QUALITY IN MARES

, 2010
Athletic mares are commonly utilized in an embryo transfer regimen during the breeding season, which allows owners to continue to train and compete with these animals.
J. Gibbons, R. Smith, J. Anton, K. Vernon, D. Kelley, C. Mortensen   +5 more
core   +1 more source

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

Molecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel, Izabela Kubiak, Lena Rutkowska, Żaneta Kasprzyk, Łukasz Kępczyński, Michał Bednarek, Dariusz Sobieraj, Jacek Wilkosz, Piotr Kania, Adam Jędrzejczyk, Bogdan Kałużewski, Agnieszka Gach, Tadeusz Kałużewski   +12 more
wiley   +1 more source

The use of autologous platelet-rich plasma in embryo culture to obtain high-quality embryos

Scientific Reports
Transferring high-quality embryos is crucial for in vitro fertilization success, as they lead to better clinical pregnancy and live birth outcomes.
Yeo Jin Rhee, Jae Kyun Park, So-Yeon Ahn, Soyoung Bang, Jung Hoon Kim, Min Kyoung Kim, Woo Sik Lee   +6 more
doaj   +1 more source

Early embryo cleavage is a strong indicator of embryo quality in human IVF [PDF]

Human Reproduction, 2001
In order to decrease multiple birth rates without decreasing birth rates overall, it is important to increase the capability of selecting the most optimal embryos for transfer. It has been shown that human embryos which cleave early, i.e. complete the first mitotic division within 25-27 h post insemination, provide higher pregnancy and implantation ...
K, Lundin, C, Bergh, T, Hardarson
openaire   +2 more sources

Cytokines in culture media of preimplantation embryos during in vitro fertilization: Impact on embryo quality

, 2021
Cytokine support of embryonic development includes promotion of implantation and protection of blastomeres from cell stress and apoptosis. Correlations between embryo quality and concentrations of specific cytokines in culture media of human embryos have
서석교, 최영식, 이병석, 박주현, 김희연, 조시현, 이인하, 김혜인, 이재훈, 윤보현, 백혜원, 박윤정, 안소현   +12 more
core   +1 more source