Results 61 to 70 of about 17,740,973 (321)

Legislating Respect: A Pro-Choice Feminist Analysis of Embryo Research Restrictions in Canada

open access: yes, 2012
This article investigates the impact of legislating respect and dignity for the embryo in vitro on the legal and cultural status of the embryo in utero.
Maneesha Deckha
semanticscholar   +1 more source

Role of gaseous giants in the dynamical evolution of terrestrial planets and water delivery in the habitable zone [PDF]

open access: yes, 2018
In the present research, we study the effects of a single giant planet in the dynamical evolution of water-rich embryos and planetesimals, located beyond the snow line of systems around Sun-like stars, in order to determine what kind of terrestrial-like planets could be formed in the habitable zone (hereafter HZ) of these systems.
arxiv   +1 more source

Fertility outcomes in women after controlled ovarian stimulation with gonadotropin releasing hormone agonist long protocol: fresh versus frozen embryo transfer

open access: yesBMC Pregnancy and Childbirth, 2021
Background Along with progress in embryo cryopreservation, especially the vitrification, freeze all strategy has become more acceptable than ever. Some studies have found comparable or higher live birth rate with frozen embryo transfer (FET) than with ...
Xiaoyan Ding   +6 more
doaj   +1 more source

MET variants with activating N‐lobe mutations identified in hereditary papillary renal cell carcinomas still require ligand stimulation

open access: yesMolecular Oncology, EarlyView.
MET variants in the N‐lobe of the kinase domain, found in hereditary papillary renal cell carcinoma, require ligand stimulation to promote cell transformation, in contrast to other RTK variants. This suggests that HGF expression in the microenvironment is important for tumor growth in such patients. Their sensitivity to MET inhibitors opens the way for
Célia Guérin   +14 more
wiley   +1 more source

Intrauterine Hyperglycemia Alters the Metabolomic Profile in Fetal Mouse Pancreas in a Gender-Specific Manner

open access: yesFrontiers in Endocrinology, 2021
Mounting evidence has shown that intrauterine hyperglycemia exposure during critical stages of development may be contributing to the increasing prevalence of diabetes.
Hong Zhu   +21 more
doaj   +1 more source

Planetary formation and water delivery in the habitable zone around solar-type stars in different dynamical environments [PDF]

open access: yesA&A 609, A76 (2018), 2017
Aims. We study the formation and water delivery of planets in the habitable zone (HZ) around solar-type stars. In particular, we study different dynamical environments that are defined by the most massive body in the system. Methods. First of all, a semi-analytical model was used to define the mass of the protoplanetary disks that produce each of the ...
arxiv   +1 more source

CircCCNB1 inhibits vasculogenic mimicry by sequestering NF90 to promote miR‐15b‐5p and miR‐7‐1‐3p processing in nasopharyngeal carcinoma

open access: yesMolecular Oncology, EarlyView.
CircCCNB1 expression is down‐regulated in nasopharyngeal carcinoma (NPC); thus, less NF90 protein is bound to circCCNB1 and more binds to pri‐miRNAs, blocking their (pri‐miRNAs) binding to DGCR8 and inhibiting the processing and generation of miR‐15b‐5p/miR‐7‐1‐3p. Furthermore, decreased miR‐15b‐5p/miR‐7‐1‐3p promotes the expression of the target genes
Chunmei Fan   +6 more
wiley   +1 more source

Current Status of Genetically Modified Pigs That Are Resistant to Virus Infection

open access: yesViruses, 2022
Pigs play an important role in agriculture and biomedicine. The globally developing swine industry must address the challenges presented by swine-origin viruses, including ASFV (African swine fever virus), PRRSV (porcine reproductive and respiratory ...
Hongming Yuan   +7 more
doaj   +1 more source

Linking planetary embryo formation to planetesimal formation I: The impact of the planetesimal surface density in the terrestrial planet zone [PDF]

open access: yes, 2020
The growth time scales of planetary embryos and their formation process are imperative for our understanding on how planetary systems form and develop. They determine the subsequent growth mechanisms during the life stages of a circumstellar disk.
arxiv   +1 more source

Transcriptome‐wide analysis of circRNA and RBP profiles and their molecular relevance for GBM

open access: yesMolecular Oncology, EarlyView.
CircRNAs are differentially expressed in glioblastoma primary tumors and might serve as therapeutic targets and diagnostic markers. The investigation of circRNA and RNA‐binding proteins (RBPs) interactions shows that distinct RBPs play a role in circRNA biogenesis and function.
Julia Latowska‐Łysiak   +14 more
wiley   +1 more source

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