This study demonstrates that cholesterol in messenger RNA‐lipid nanoparticles (mRNA‐LNPs) can be completely replaced with an immunopotentiating lipid, i.e., a synthetic analogue of the C‐type lectin receptor agonist monomycoloyl glycerol (MMG‐1), without compromising physicochemical properties, in vivo transfection efficiency, and immunogenicity of the
Abhijeet G. Lokras+19 more
wiley +1 more source
Application of three-dimensional scanning in rebuilding female reproductive system model for embryo transfer training [PDF]
Objective To explore three-dimensional scanning and reconstruction technology in embryo transfer training. Methods Two sets of female reproductive system models, standard and cervical stenosis, were reconstructed with three-dimensional scanner, data ...
RAO Jin-peng, QIU Feng, CAI Yi-ting, WEI Kai, JIN Min, JIN Fan
doaj
Neoplastic transformation of mouse C3H 10T1/2 and Syrian hamster embryo cells by heavy ions [PDF]
C3H 10T1/2 mouse-embryo fibroblasts were used for transformation experiments to study the effectiveness of various heavy ions with energies up to 20 MeV/u and LET values from 170 to 16.000 keV/μm.
A.M. Kellerer+24 more
core +1 more source
Studies on the fractionation of total transfer ribonucleic acid and purification of an alanine transfer ribonucleic acid from chick embryo [PDF]
M. P. J. S. Anandaraj+1 more
openalex +1 more source
Transducer Materials Mediated Deep Brain Stimulation in Neurological Disorders
This review discusses advanced transducer materials for improving deep brain stimulation (DBS) in neurological disorders. These materials respond to light, ultrasound, or magnetic fields, enabling precise, less invasive neuromodulation. Their stimulus‐responsive properties enhance neural control and adaptive therapy, paving the way for next‐generation ...
Di Zhao+5 more
wiley +1 more source
The Influence Of Intrauterine Pressure On Embryo Retention In A Catheter After Embryo Transfer
The retention of the embryo in the transfer catheter after embryo transfer (ET) during in vitro fertilization is a very common phenomenon, encountered by even the most experienced operators, and embryos retained in the transfer catheter or its sleeve ...
Małgorzata Kozikowska+5 more
doaj +1 more source
Understanding the ethical concerns that have shaped European regulation of human embryonic stem cell research [PDF]
Human embryonic stem cell research has generated much hope, but also fear and repulsion. National legislators, as well as the European Parliament, the European Patent Office and the European Court of Justice have had to make decisions relating to what is
Mertes, Heidi
core
PRODUCTION OF TWIN CALVES BY NON‐SURGICAL EMBRYO TRANSFER [PDF]
D. Jillella, R. J. Eaton, A. Baker
openalex +1 more source
Machine Learning Guided Design of Nerve‐On‐A‐Chip Platforms with Promoted Neurite Outgrowth
Compared to labor‐intensive trial‐and‐error experimentation, a machine learning (ML)‐guided workflow, incorporating cell viability assays, data augmentation, ensemble modeling, and model interpretation, is developed to accelerate nerve‐on‐a‐chip optimization and uncover data‐driven design principles.
Tsai‐Chun Chung+8 more
wiley +1 more source
The pre‐internalization phase of endocytosis remains poorly characterized at single‐cell levels. Single‐cell pre‐internalization mechanics are investigated using advanced robotic techniques. Cancer cells exhibit biphasic adhesion – rapid initial binding followed by reinforcement – while fibroblasts show gradual engagement.
Houari Bettahar+6 more
wiley +1 more source