Results 81 to 90 of about 112,190 (308)

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

FEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim, Marco Corazzari, Iman Osman, Jane Armstrong, Noel Carter   +4 more
wiley   +1 more source

Endometrial transcriptome profiling of patients with recurrent implantation failure during hormone replacement therapy cycles

Frontiers in Endocrinology
BackgroundThe molecular mechanisms underlying window of implantation (WOI) displacement in patients with recurrent implantation failure (RIF) remain unclear.
Wen-bi Zhang, Jue Li, Qing Li, Xiang Lu, Jun-ling Chen, Lu Li, Hua Chen, Wei Fu, Jiu-cheng Chen, Bing-jie Lu, Han Wu, Xiao-xi Sun, Xiao-xi Sun   +12 more
doaj   +1 more source

Use of Doppler ultrasonography in embryo transfer programs: feasibility and field results

, 2018
The intensive use of Doppler ultrasonography in several studies in the last decade allowed the characterization of vascular perfusion and the estimation of function of the reproductive organs and tissues along the estrous cycle and pregnancy in cattle ...
Silva, Julio Barboza, Moraes Vasconcelos, Jose Luiz [UNESP], Pugliesi, Guilherme, Rocha, Cecilia Constantino, Gontijo Pellegrino, Carlos Augusto, Binelli, Mario, Melo, Gabriela Dalmaso de, Ataide, Gilmar Arantes, Motta, Igor Garcia   +8 more
core   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

Aging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang, Zhong Fan, Runmeng Liu, Xiaotian Zhang   +3 more
wiley   +1 more source

HLA-G MOLECULES: FROM EMBRYO IMPLANTATION TO OOCYTE MATURATION

, 2009
Background Assisted reproduction technique (ART) pregnancy rates have not changed in recent years and an increased risk of twins, triplets or higher order pregnancies leads to a perinatal mortality and morbidity.
Rizzo, Roberta
core  

Super‐Refractory Status Epilepticus (SRSE) in a Patient With Compound Heterozygous OPA1 Variants: Case Report and Literature Review

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi, Lara Basovic, Christopher Michael McGraw   +2 more
wiley   +1 more source

Influence of some fatty acids and cholesterol addition to semen extender on freezability and in itro fertilizinic potentials of ram spermatozoa [PDF]

Assiut Veterinary Medical Journal, 2004
M.R. Badr, Mary G. Abdel-Malak, Mona H. Shaker   +2 more
doaj   +1 more source

Early Clinical, Imaging, and Pathological Characteristics of SRPK3/TTN‐Digenic Myopathy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective SRPK3/TTN‐digenic myopathy was recently established as a skeletal muscle myopathy caused by digenic inheritance. This study characterizes the early clinical presentation of SRPK3/TTN‐digenic myopathy in one previously reported and seven newly identified pediatric patients.
Rotem Orbach, Sandra Donkervoort, Carola Hedberg‐Oldfors, Giovanni Baranello, Dimah Saade, Precilla D'Souza, Ruchee Patel, Eva Michael, A. Reghan Foley, Diana Bharucha‐Goebel, S. Jin Haugland, Meghan McAnally, Omer Abdul Hamid, Katherine Chao, Ellen F. Macnamara, Alan H. Beggs, Anna Sarkozy, Juliane Mueller, Steven A. Moore, Richard S. Finkel, Cynthia J. Tifft, Francesco Muntoni, Anders Oldfors, Carsten G. Bönnemann   +23 more
wiley   +1 more source

INFLUENCE OF ANTIOXIDAYTS ON FREEZABILITY, IN VITRO FERTILIZINC POTENTIAL AND CONCEPION RATE OF BUFFALO SPERMATOZOA [PDF]

Assiut Veterinary Medical Journal, 2003
M.R. Badr, Maha S. Ziada, G.M. Darwish, A.A. Nasra   +3 more
doaj   +1 more source