Results 61 to 70 of about 2,320,471 (297)
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Efficiency of Semen Cryopreservation in Stallions
Animals, 2020 Differences in the cryotolerance of spermatozoa exist among stallions, but it remains to be determined to what extent such differences are affected by breed.
Jörg Aurich +3 more
doaj +1 more source
BACTERIOLOGICAL STUDIES OF ENDOMETRITIS AS A MAIN CAUSE FOR REPRODUCTIVE AND FERTILITY PROBLEMS IN SHE-CAMEL [PDF]
Assiut Veterinary Medical Journal, 2012 A total of 54 femal camels with a history of conception failure were examined through transrectal palpation, ultrasonography and vaginal explorations.
A.M. NABIH, R.H. OSMAN
doaj +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
AnimalTo achieve future sustainable high-quality Wagyu beef production, it is important to provide a novel approach to genetically improve Japanese Black cattle.
S. Ogawa +6 more
doaj +1 more source
INFLUENCE OF BOVINE VIRAL DIARRHEA VIRUS INFECTION ON IN VITRO BUFFALO EMBRYOS PRODUCTION AND HISTOPATHOLOGICAL FINDINGS IN THEIR OVARIES [PDF]
Assiut Veterinary Medical Journal, 2005 The objectives of this study were isolation and identification of bovine viral diarrhea virus (BVDV) from follicular fluid of buffalo ovaries by indirect immunofluoresence antibody technique (IFA) and reverse transcription-polymerase chain reaction (RT ...
M.R. BADR +2 more
doaj +1 more source
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Molecular Oncology, EarlyView.This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi +6 more
wiley +1 more source
Nuclear reprogramming: kinetics of cell cycle and metabolic progression as determinants of success [PDF]
, 2012 Establishment of totipotency after somatic cell nuclear transfer (NT) requires not only reprogramming of gene expression, but also conversion of the cell cycle from quiescence to the precisely timed sequence of embryonic cleavage.
Franchesca Dawn Houghton (171722) +44 more
core +2 more sources
Molecular Oncology, EarlyView.We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth +17 more
wiley +1 more source