Results 51 to 60 of about 2,320,471 (297)

Epigenetic reprogramming of lineage switching in cancer

open access: yesFEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı   +4 more
wiley   +1 more source

Influence Of Combinations Of Some Permeable Cryoprotectants With Chicken And Duck Egg Yolks On Freezability And Dna Integrity Of Buffalo Spermatozoa

open access: yesJournal of Applied Veterinary Sciences, 2020
The present study aimed to investigate the cryoprotective effect of different combinations of glycerol (G), dimethyl sulphoxide (DMSO) and dimethylformamide (DMF) with chicken egg yolk (CEY) and duck egg yolk (DEY) on freezability of buffalo spermatozoa.
Rawash, Z.M.   +3 more
doaj   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

open access: yesFEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante   +10 more
wiley   +1 more source

EFFECT OF HCG WITH INTRAVAGINAL SPONGES ON REPRODUCTIVE PERFORMANCE IN AWASSI EWES DURING ESTRUS SYNCHRONIZATION [PDF]

open access: yesAssiut Veterinary Medical Journal, 2014
One hundred and nineteen Awassi ewes, 3 to 5 years old, treated with vaginal sponges. eCG and hCG, were used to determine their response for estrus synchronization and pregnancy rates during anestrous season.
NASOUH KHAZNADAR   +2 more
doaj   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

open access: yesFEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk   +11 more
wiley   +1 more source

Sperm Quality during Storage Is Not Affected by the Presence of Antibiotics in EquiPlus Semen Extender but Is Improved by Single Layer Centrifugation

open access: yesAntibiotics, 2017
Contamination of semen with bacteria arises during semen collection and handling. This bacterial contamination is typically controlled by adding antibiotics to semen extenders but intensive usage of antibiotics can lead to the development of bacterial ...
Ziyad Al-Kass   +6 more
doaj   +1 more source

EFFECT OF DIFFERENT L-ARGININE CONCENTRATIONS ON IN VITRO BUFFALO SEMEN FERTILIZING POTENTIALS [PDF]

open access: yesAssiut Veterinary Medical Journal, 2016
Sperm capacitation and acrosome reaction are essential for fertilization. L-Arginine plays an important role in the physiology of spermatozoa and has been shown to enhance their metabolism and maintain their motility.
MONTASER, A., BADR, M.R.
doaj   +1 more source

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

open access: yesFEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux   +7 more
wiley   +1 more source

Differences in Endocrine and Cardiac Changes in Mares and Her Fetus before, during, and after Parturition in Horses of Different Size

open access: yesAnimals, 2020
Equine fetomaternal monitoring is based on endocrine and cardiac parameters which may differ among small, medium-size, and full-size horses. Therefore, Shetland (n = 6), Haflinger (n = 8), and Warmblood pregnancies (n = 9) were studied during late ...
Christina Nagel   +3 more
doaj   +1 more source

EFFECTS OF L-CARNITINE ON MORPHOLOGY AND ANTIOXIDANT ENZYMES AND DNA INTEGRITY OF CRYOPRESERVED BUFFALO SPERMATOZOA [PDF]

open access: yesAssiut Veterinary Medical Journal, 2017
Cryopreservation induces sub lethal damage to the spermatozoa, thereby reduce their fertile life. There are some biochemical additives that may enhance buffalo semen freezability; L-carnitine is one of these biochemical semen additives.
BADR, M.A.   +4 more
doaj   +1 more source

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