Results 71 to 80 of about 2,320,471 (297)

HLA-G MOLECULES: FROM EMBRYO IMPLANTATION TO OOCYTE MATURATION [PDF]

, 2009
Background Assisted reproduction technique (ART) pregnancy rates have not changed in recent years and an increased risk of twins, triplets or higher order pregnancies leads to a perinatal mortality and morbidity.
Rizzo, Roberta
core  

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

FEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee, Giulia Zanetti, Bram van den Broek, Kees Jalink   +3 more
wiley   +1 more source

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

FEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour, Christine Volmert, Valentina Piano   +2 more
wiley   +1 more source

The C‐terminal region of KIF26B is indispensable for nephron progenitor condensation and kidney formation in mice

FEBS Open Bio, EarlyView.
KIF26B plays an important role in kidney development. We engineered mice lacking the C‐terminal region of KIF26B and found severe kidney defects, including bilateral renal agenesis, similar to full Kif26b knockout mice. The mutation disrupted nephron progenitor condensation and reduced Gdnf‐Wnt11 signaling, showing that the KIF26B C‐terminal region is ...
Yuta Yamamura, Kengo Furuichi, Hiromitsu Akamatsu, Naoki Yamamoto, Sako Keisuke, Akihiko Koshino, Taichiro Minami, Megumi Oshima, Akinori Hara, Norihiko Sakai, Miho Shimizu, Kenta Takahashi, Minako Yamamura, Shin‐ichi Horike, Takiko Daikoku, Kenichi Harada, Yohei Shinmyo, Hiroshi Kawasaki, Takashi Wada, Yasunori Iwata   +19 more
wiley   +1 more source

Individualized luteal support according to serum progesterone levels during programmed artificial frozen embryo transfer cycles

, 2022
reservedNei cicli FET artificiali, data l’assenza di un corpo luteo endogeno, la supplementazione luteale con progesterone (P4) è mandatoria, essendo questo l’ormone principalmente responsabile di un’adeguata predecidualizzazione dell’endometrio, che si
BRAGGION, GIULIA
core  

The chicken embryo and its micro environment during egg storage and early incubation [PDF]

, 2008
When egg storage periods are prolonged (>7 days), hatchability and chick quality declines. The reason for this decline has been investigated, but is still not completely understood.
Brand, H., van den, Kemp, B., Meijerhof, R., Reijrink, I.A.M.   +3 more
core   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Endometrial stromal cells of women with recurrent miscarriage fail to discriminate between high- and low-quality human embryos [PDF]

, 2012
Background The aetiology of recurrent miscarriage (RM) remains largely unexplained. Women with RM have a shorter time to pregnancy interval than normally fertile women, which may be due to more frequent implantation of non-viable embryos.
Weimar, Charlotte H. E., Gellersen, Birgit, Heijnen Cobi J., Johanna M T de Vreeden-Elbertse, Jan J. Brosens (109247), de Vreeden-Elbertse Johanna M. T., de Vreeden-Elbertse, Johanna M.T., Nick S Macklon, Macklon Nick S., Kavelaars, Annemieke, Charlotte H. E. Weimar (148304), Nick S. Macklon (148320), Jan J Brosens, Weimar Charlotte H. E., Gellersen Birgit, Cobi J. Heijnen (148314), Brosens Jan J., Macklon, Nick S., Weimar, Charlotte H.E., Kavelaars Annemieke, Cobi J Heijnen, Charlotte H E Weimar, Birgit Gellersen (148307), de Vreeden-Elbertse, Johanna M. T., Brosens, Jan J., Heijnen, Cobi J., Annemieke Kavelaars, Annemieke Kavelaars (12570), Birgit Gellersen, Johanna M. T. de Vreeden-Elbertse (148309)   +29 more
core   +2 more sources

Small RNA pathways in mammalian oocytes

FEBS Open Bio, EarlyView.
Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley   +1 more source

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

FEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim, Marco Corazzari, Iman Osman, Jane Armstrong, Noel Carter   +4 more
wiley   +1 more source