ELECTRON MICROSCOPIC EXAMINATION OF THE SITES OF NUCLEAR RNA SYNTHESIS DURING AMPHIBIAN EMBRYOGENESIS [PDF]
, 1965 Shuichi Karasaki
openalex +1 more source
The Heterotaxy Gene CCDC11 Is Important for Cytokinesis via RhoA Regulation
Cytoskeleton, EarlyView.ABSTRACT Mutations in CCDC11 (cfap53) have been identified in multiple patients with heterotaxy (Htx), a disorder of left–right (LR) patterning of the internal organs. In Xenopus, depletion of Ccdc11 causes defects in LR patterning, recapitulating the patient phenotype. Upon Ccdc11 depletion, monociliated cells of the Left–Right Organizer (LRO) exhibit
Saurabh S. Kulkarni +9 more
wiley +1 more source
The small intestinal mucosa and its stem cells
Journal of Pediatric and Neonatal Individualized Medicine, 2016 In the first part of this review a brief summary of the embryology and histology of the gastrointestinal tract is provided. In the second part intestinal stem cells (ISCs) are discussed. Several signaling pathways play a crucial role in the crypt base in
Rossano Ambu +10 more
doaj +1 more source
Major changes in the core developmental pathways of nematodes: Romanomermis culicivorax reveals the derived status of the Caenorhabditis elegans model [PDF]
arXiv, 2013 Background Despite its status as a model organism, the development of Caenorhabditis elegans is not necessarily archetypical for nematodes. The phylum Nematoda is divided into the Chromadorea (indcludes C. elegans) and the Enoplea. Compared to C. elegans, enoplean nematodes have very different patterns of cell division and determination.
arxiv
Single Cells, Coconut Milk, and Embryogenesis in vitro [PDF]
, 1966 Walter Halperin
openalex +1 more source
Phosphorylation at the Helm: Kinase‐Mediated Regulation of Primary Cilia Assembly and Disassembly
Cytoskeleton, EarlyView.ABSTRACT The primary cilium serves as an antenna of most vertebrate cells and is important for conveying cues from several signaling pathways into appropriate cellular responses during development and homeostasis. Cilia assembly and disassembly processes are thought to be strictly controlled; however, the precise nature of molecular events underlying ...
Andrea Lacigová, Lukáš Čajánek
wiley +1 more source
Prediction of Cellular Identities from Trajectory and Cell Fate Information [PDF]
arXivDetermining cell identities in imaging sequences is an important yet challenging task. The conventional method for cell identification is via cell tracking, which is complex and can be time-consuming. In this study, we propose an innovative approach to cell identification during early $\textit{C. elegans}$ embryogenesis using machine learning.
arxiv
Hallmarks of Neuroblastoma—Pathophysiology, Diagnosis, and Therapeutic Interventions
Cancer Nexus, EarlyView.ABSTRACT Neuroblastoma, the most common extracranial solid tumor in childhood, continues to challenge clinicians and researchers because of its heterogeneous nature and complex pathophysiology. Recent breakthroughs in molecular profiling revealed intricate genetic alterations driving tumor progression, necessitating an updated perspective on the ...
Abhimanyu Thakur, Anne Dijkstra
wiley +1 more source
Developmental and genomic architecture of plant embryogenesis: from model plant to crops
Plant Communications, 2021 Embryonic development represents an important reproductive phase of sexually reproducing plant species. The fusion of egg and sperm produces the plant zygote, a totipotent cell that, through cell division and cell identity specification in early ...
Alma Armenta-Medina +6 more
doaj
A simple mechanochemical model for calcium signalling in embryonic epithelial cells [PDF]
arXiv, 2019 Calcium (Ca2+) signalling is one of the most important mechanisms of information propagation in the body. In embryogenesis the interplay between Ca2+ signalling and mechanical forces is critical to the healthy development of an embryo but poorly understood.
arxiv