Results 121 to 130 of about 137,546 (322)
Developmental Dynamics, EarlyView.Abstract Background Environmental influence is critical for embryogenesis but is significantly under‐appreciated under lab conditions, which are not typically designed to robustly test environmental variability. Here, we report environmental effects on the developmental phenotype of zebrafish lacking the transcription factor Grainyhead‐like 3 (grhl3 ...
Nishanthi Mathiyalagan +5 more
wiley +1 more source
Major changes in the core developmental pathways of nematodes: Romanomermis culicivorax reveals the derived status of the Caenorhabditis elegans model [PDF]
arXiv, 2013 Background Despite its status as a model organism, the development of Caenorhabditis elegans is not necessarily archetypical for nematodes. The phylum Nematoda is divided into the Chromadorea (indcludes C. elegans) and the Enoplea. Compared to C. elegans, enoplean nematodes have very different patterns of cell division and determination.
arxiv
Single Cells, Coconut Milk, and Embryogenesis in vitro [PDF]
, 1966 Walter Halperin
openalex +1 more source
Developmental Dynamics, EarlyView.Abstract Background The emergence of multicellularity in animals marks a pivotal evolutionary event, which was likely enabled by molecular innovations in the way cells adhere and communicate with one another. β‐Catenin is significant to this transition due to its dual role as both a structural component in the cadherin–catenin complex and as a ...
Brian M. Walters +5 more
wiley +1 more source
Prediction of Cellular Identities from Trajectory and Cell Fate Information [PDF]
arXivDetermining cell identities in imaging sequences is an important yet challenging task. The conventional method for cell identification is via cell tracking, which is complex and can be time-consuming. In this study, we propose an innovative approach to cell identification during early $\textit{C. elegans}$ embryogenesis using machine learning.
arxiv
A simple mechanochemical model for calcium signalling in embryonic epithelial cells [PDF]
arXiv, 2019 Calcium (Ca2+) signalling is one of the most important mechanisms of information propagation in the body. In embryogenesis the interplay between Ca2+ signalling and mechanical forces is critical to the healthy development of an embryo but poorly understood.
arxiv
Dynamics of primary cilia in endothelial and mesenchymal cells throughout mouse lung development
Developmental Dynamics, EarlyView.Abstract Cilia are specialized structures found on a variety of mammalian cells, with variable roles in the transduction of mechanical and biological signals (by primary cilia, PC), as well as in the generation of fluid flow (by motile cilia). Their critical role in the establishment of a left–right axis in early development is well described, as well ...
Stephen Spurgin +8 more
wiley +1 more source
WIREs RNA, Volume 14, Issue 1, January/February 2023., 2023 Genetic oscillators play crucial roles in development. The hairy/Enhancer of split gene family (Hes/her) undergo cell‐autonomous genetic oscillations to regulate the timing of vertebrate segmentation and neural cell proliferation and differentiation. mRNA stability and translation are tightly regulated to maintain oscillatory expression.
Monica C. Blatnik +2 more
wiley +1 more source
Lineage labeling with zebrafish hand2 Cre and CreERT2 recombinase CRISPR knock‐ins
Developmental Dynamics, EarlyView.Abstract Background The ability to generate endogenous Cre recombinase drivers using CRISPR‐Cas9 knock‐in technology allows lineage tracing, cell type‐specific gene studies, and in vivo validation of inferred developmental trajectories from phenotypic and gene expression analyses. This report describes endogenous zebrafish hand2 Cre and CreERT2 drivers
Zhitao Ming +14 more
wiley +1 more source
Developmental and genomic architecture of plant embryogenesis: from model plant to crops
Plant Communications, 2021 Embryonic development represents an important reproductive phase of sexually reproducing plant species. The fusion of egg and sperm produces the plant zygote, a totipotent cell that, through cell division and cell identity specification in early ...
Alma Armenta-Medina +6 more
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