Engineered Exosome‐Based Senolytic Therapy Alleviates Stroke by Targeting p21+CD86+ Microglia
Exploration, EarlyView.We identified a harmful immune cell type, p21+CD86+ microglia, driving post‐stroke inflammation and developed a targeted exosome‐based therapy (Que@micro‐Exo) to eliminate these cells. This innovative treatment reduced inflammation, alleviated brain damage, and improved recovery in stroke models, offering a promising strategy for stroke and other ...
Jialei Yang, Shipo Wu, Miao He
wiley +1 more source
Embryogenesis and substratum adhesion in the brown algaHormosira banksii(Turner) Decaisne [PDF]
, 1979 Margaret Forbes, N. D. Hallam
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Decoding RNA–Protein Interactions: Methodological Advances and Emerging Challenges
Advanced Genetics, EarlyView.This review provides a comprehensive comparison of RNA‐ and protein‐centric methodologies for investigating RNA–protein interactions, emphasizing their respective advantages, limitations, and suitable applications. It highlights recent technological innovations, outlines strategic method selection criteria, and addresses key challenges.
Wenkai Yi, Jian Yan
wiley +1 more source
Oligodendrogenesis in Evolution, Development and Adulthood
Glia, EarlyView.Oligodendrocytes and myelin took shape in jawed vertebrates. During development, OPCs are originated from NSCs and then undergo differentiation into mature oligodendrocytes that supply myelin. OPCs persist in the adult CNS and continue to produce oligodendrocytes and myelin. Adaptive myelination, which fine‐tunes neural circuits in response to neuronal
Hao Hu +3 more
wiley +1 more source
The Genetics of Embryogenesis in Drosophila
, 1970 Uploaded by Plazi for TaxoDros. We do not have abstracts.
openaire +4 more sources
Patterns of DNA synthesis during pollen embryogenesis in henbane. [PDF]
, 1977 V. Raghavan
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Bilateral Thyroid Ima Arteries Arising From the Brachiocephalic Trunk: A First Case Report
Head &Neck, EarlyView.ABSTRACT Rationale Bilateral thyroid ima artery (TIA) arising from the brachiocephalic trunk is an extremely rare anatomical variation, with no prior cases reported. Recognizing such vascular anomalies is crucial for optimizing surgical outcomes in thyroid and mediastinal procedures, as failure to identify these variations can lead to severe ...
Ziqiang Wang +5 more
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ANALYSIS OF CELL PROLIFERATION DURING EARLY EMBRYOGENESIS [PDF]
, 1976 Akio Suzuki +2 more
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Zinner Syndrome Presenting With Chronic Pelvic Pain and Ejaculatory Dysfunction
IJU Case Reports, EarlyView.ABSTRACT Introduction Zinner Syndrome is a rare congenital anomaly involving unilateral renal agenesis, ipsilateral seminal vesicle cyst, and ejaculatory duct obstruction. We report a symptomatic case managed conservatively. Case Presentation A 19‐year‐old male presented with 6 months of intermittent pelvic pain, dysuria, and ejaculatory discomfort ...
Tejasvi Patil +9 more
wiley +1 more source
Predicting Future States with Spatial Point Processes in Single Molecule Resolution Spatial Transcriptomics [PDF]
arXivIn this paper, we introduce a pipeline based on XGboost to predict the future distribution of cells that are expressed by the Sog-D gene (active cells) in both the Anterior to posterior (AP) and the Dorsal to Ventral (DV) axis of the Drosophila in embryogenesis process.
arxiv