Results 251 to 260 of about 338,049 (387)

Calpain Proteases and the Evolving Signaling Network in Insect Embryonic Patterning

open access: yesJournal of Experimental Zoology Part B: Molecular and Developmental Evolution, EarlyView.
Insect embryonic Dorsal‐Ventral (DV) patterning relies on the BMP and Toll pathways to different extents. Calcium‐dependent cystein proteases of the Calpain family also exert an important function to pattern the DV axis. In Drosophila, Calpain A cleaves the Cactus/IkappaB inhibitor and modifies Toll signals in ventral regions of the embryo. In Rhodnius
Alison Julio, Helena Araujo
wiley   +1 more source

Analysis of Gene Expression in Aedes aegypti Suggests Changes in Early Genetic Control of Mosquito Development

open access: yesJournal of Experimental Zoology Part B: Molecular and Developmental Evolution, EarlyView.
ABSTRACT Aedes aegypti, a critical vector for tropical diseases, poses significant challenges for studying its embryogenesis due to difficulties in removing its rigid chorion and achieving effective fixation for in situ hybridization. Here, we present novel methodologies for fixation, dechorionation, DAPI staining, and in situ hybridization, enabling ...
Renata Coutinho‐dos‐Santos   +8 more
wiley   +1 more source

Recently Evolved, Stage‐Specific Genes Are Enriched at Life‐Stage Transitions in Flies

open access: yesJournal of Experimental Zoology Part B: Molecular and Developmental Evolution, EarlyView.
We discovered that 20%–30% of protein‐coding genes in Drosophila melanogaster and Aedes aegypti are only expressed during specific stages of development. Surprisingly, many of these stage‐specific genes are newly evolved, unique to flies and mosquitoes, shedding light on how insect development has evolved over time.
Andreas Remmel   +3 more
wiley   +1 more source

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