Results 181 to 190 of about 240,921 (300)
Gestational sac ellipticity index measured at ≤ 7 weeks' gestation as a predictor of first-trimester embryonic demise: a retrospective cohort study. [PDF]
Zhao W, Yin J.
europepmc +1 more source
An Opto‐Actuated Hydrogel for Cell Mechanoactuation and Real‐Time Force Monitoring
Researchers developed a mechanoactuated hydrogel interface where nanomachines exert forces on adhesion receptors and allow monitoring of traction force responses in real time. They demonstrate reversible talin recruitment, enhanced F‐actin polymerization, and a reduction in cell traction force when force is locally applied to focal adhesions of ...
Rinku Kumar +6 more
wiley +1 more source
Disruption of the Placenta-Brain Axis in Transgenic Mice Lacking Serotonin Transporter (SERT) in Trophoblast Cells. [PDF]
Ellenberger DT +10 more
europepmc +1 more source
Fetal Fibroblast Heterogeneity Defines Dermal Architecture during Human Embryonic Skin Development
Noriko Morioka +2 more
openalex +1 more source
Lipid Droplet‐Localized Spindle Apparatus Coiled‐Coil Protein 1 Regulates Lipid Droplet Distribution
SPDL1‐L, a long isoform of SPDL1, is identified as a bona fide lipid droplet‐associated protein that acts as a dynein adaptor to drive perinuclear clustering of lipid droplets. By linking lipid droplets to the microtubule network, SPDL1‐L extends the function of SPDL1 beyond mitosis and contributes to lipid droplet organization and nuclear remodeling ...
Honggang Su +10 more
wiley +1 more source
How Early-Life Programming During Embryogenesis Imprints Cellular Memory. [PDF]
Alfian NF +9 more
europepmc +1 more source
Hydrogen voltage gated channel 1 (HVCN1) is upregulated in microglia of both ALS patients and its mouse model. HVCN1 deficiency enhances microglial migration via suppressing Akt signaling, promotes neurotrophic capacity and motor function, and prolongs survival of the SOD1G93A ALS mice. This study identifies HVCN1 as a novel, promising druggable target
Fan Wang +16 more
wiley +1 more source
The Impact of Maternal Gut Dysbiosis on Embryo/Fetus Development. [PDF]
Fan N, Shen Y, Yang X, Ma S, Wang G.
europepmc +1 more source
This study identifies a new viral mechanism by a viral protein σ3 that functions as a vTR to suppress NF‐κB gene expression via its direct interaction with the host helicase DHX9. Through their interaction, σ3 not only impairs the initial recruitment of Pol II but also affects Pol II pause‐release and ultimately suppresses NF‐κB gene expression ...
Xueyang Pang +12 more
wiley +1 more source

