Results 31 to 40 of about 267,193 (260)

High-definition ultrasonography for evaluation of embryonic and fetal development in bitch

Arquivo Brasileiro de Medicina Veterinária e Zootecnia, 2022
In women, high-definition ultrasonography provides high-quality images of normal and diseased tissues throughout pregnancy, however there are no veterinary studies describing the use of this technology in pregnant dogs.
M.C. Maronezi, A.P.R. Simões, R.A.R. Uscategui, R.K. Carneiro, B. Gasser, P. Silva, G.S. Maciel, I.C.K. Cruz, W.R. Vicente, M.A.R. Feliciano   +9 more
doaj   +1 more source

Fetal and trophoblast PI3K p110α have distinct roles in regulating resource supply to the growing fetus in mice

eLife, 2019
Studies suggest that placental nutrient supply adapts according to fetal demands. However, signaling events underlying placental adaptations remain unknown.
Jorge López-Tello, Vicente Pérez-García, Jaspreet Khaira, Laura C Kusinski, Wendy N Cooper, Adam Andreani, Imogen Grant, Edurne Fernández de Liger, Brian YH Lam, Myriam Hemberger, Ionel Sandovici, Miguel Constancia, Amanda N Sferruzzi-Perri   +12 more
doaj   +1 more source

First-trimester utero-placental (vascular) development and embryonic and fetal growth: The Rotterdam periconception cohort [PDF]

, 2021
Introduction: Impaired placental development is a major cause of fetal growth restriction (FGR) and early detection will therefore improve antenatal care and birth outcomes.
Koning, A. H.J.; id_orcid, Koster, M. P.H., Kropman, A. T.M., Steegers, E. A.P., Steegers-Theunissen, R. P.M.; id_orcid, de Vos, E. S., Steegers-Theunissen, R. P.M., Reijnders, I. F., Mulders, A. G.M.G.J., Rousian, M., Koning, A. H.J., Willemsen, S. P.   +11 more
core   +2 more sources

Vascular Growth in the Fetal Lung [PDF]

, 2011
The structure of the lung is truly remarkable. It is primarily composed of three branched tubular networks (the airway, pulmonary artery and vein, bronchial artery and vein) which supply blood and air to the site of gas exchange and which maintain ...
Stephen C. Land, Stephen C., Land, Stephen; id_orcid   +2 more
core   +1 more source

Animal models of fetal growth restriction: Considerations for translational medicine. [PDF]

, 2015
Fetal growth restriction (FGR) is the failure of a fetus to reach its full genetic growth potential. It occurs in up to 8% of pregnancies, and after premature birth is the second leading cause of infant mortality and morbidity.
David, AL, Swanson, AM, David, A.L., Swanson, A.M.   +3 more
core   +1 more source

Comparative Analysis of Nuclear Transfer Embryo Derived Mouse Embryonic Stem Cells. Part II: Gene regulation [PDF]

, 2012
In a mouse model nuclear transfer embryo-derived embryonic stem cell lines (ntESCs) of various genetic backgrounds and donor cell types were compared with reference ESCs and analyzed comprehensively at molecular level as a second part of a larger study ...
Julianna Kobolak, Geißler, S., Mamo, S., Horsch, Marion, Horsch, M., Andras Dinnyes, Geissler, Sandra, Mamo, Solomon, Marion Horsch, Kobolak, J., Beckers, Johannes, Solomon Mamo, Kobolak, Julianna, Dinnyes, Andras, Beckers, J., Johannes Beckers, Sandra Geißler, Dinnyes, A.   +17 more
core   +1 more source

Murine exposure to gold nanoparticles during early pregnancy promotes abortion by inhibiting ectodermal differentiation

Molecular Medicine, 2018
Background Gold nanoparticles (AuNPs) have been widely studied for biomedical applications, although their safety and potential toxicity in pregnancy remains unknown.
Hui Yang, Libo Du, Guangjun Wu, Zhenyu Wu, Jeffrey A. Keelan   +4 more
doaj   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

FEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens, Brendan W. Chandler, Anna M. Schmoker, Jaye L. Weinert, Charlotte A. Kearns, Warren T. Yacawych, Amila Šemić, Alicia M. Ebert, Bryan A. Ballif   +8 more
wiley   +1 more source

Fetal and obstetrics manifestations of mitochondrial diseases

Journal of Translational Medicine
During embryonic and neonatal development, mitochondria have essential effects on metabolic and energetic regulation, shaping cell fate decisions and leading to significant short- and long-term effects on embryonic and offspring health.
Alessia Adelizzi, Anastasia Giri, Alessia Di Donfrancesco, Simona Boito, Alessandro Prigione, Emanuela Bottani, Valentina Bollati, Valeria Tiranti, Nicola Persico, Dario Brunetti   +9 more
doaj   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source