Results 41 to 50 of about 254,687 (310)

Superovulation of female mice delays embryonic and fetal development [PDF]

Human Reproduction, 2001
Mouse and human embryos, cultured in vitro, undergo a delay in development compared with those grown in vivo. This delay can be caused by suboptimal culture conditions, but possible influences of ovarian stimulation cannot be excluded. The objective of this study was to test the hypothesis that both in vitro and in vivo, preimplantation embryonic ...
I, Van der Auwera, T, D'Hooghe
openaire   +2 more sources

Fetal and trophoblast PI3K p110α have distinct roles in regulating resource supply to the growing fetus in mice

eLife, 2019
Studies suggest that placental nutrient supply adapts according to fetal demands. However, signaling events underlying placental adaptations remain unknown.
Jorge López-Tello, Vicente Pérez-García, Jaspreet Khaira, Laura C Kusinski, Wendy N Cooper, Adam Andreani, Imogen Grant, Edurne Fernández de Liger, Brian YH Lam, Myriam Hemberger, Ionel Sandovici, Miguel Constancia, Amanda N Sferruzzi-Perri   +12 more
doaj   +1 more source

Establishment of pluripotent cell lines from vertebrate species - Present status and future prospects [PDF]

, 1999
Pluripotent embryonic stem (ES) cells are undifferentiated cell lines derived from early embryos and are capable of unlimited undifferentiated proliferation in vitro.
Vassilieva, Svetlana G., Wobus, Anna M., Wolf, Eckhard, Prelle, Katja, Vassiliev, Ivan M.   +4 more
core   +1 more source

Vascular Growth in the Fetal Lung [PDF]

, 2011
The structure of the lung is truly remarkable. It is primarily composed of three branched tubular networks (the airway, pulmonary artery and vein, bronchial artery and vein) which supply blood and air to the site of gas exchange and which maintain ...
Stephen C. Land, Stephen C., Land, Stephen; id_orcid   +2 more
core   +1 more source

Murine exposure to gold nanoparticles during early pregnancy promotes abortion by inhibiting ectodermal differentiation

Molecular Medicine, 2018
Background Gold nanoparticles (AuNPs) have been widely studied for biomedical applications, although their safety and potential toxicity in pregnancy remains unknown.
Hui Yang, Libo Du, Guangjun Wu, Zhenyu Wu, Jeffrey A. Keelan   +4 more
doaj   +1 more source

Shoulder girdle formation and positioning during embryonic and early fetal human development.

PLoS ONE, 2020
Positional information on the shoulder girdle (the clavicle and scapula) is important for a better understanding of the function of the upper limb in the locomotive system as well as its associated disease pathogenesis.
Sayaka Tanaka, Rino Sakamoto, Toru Kanahashi, Shigehito Yamada, Hirohiko Imai, Akio Yoneyama, Tetsuya Takakuwa   +6 more
doaj   +2 more sources

Comparative Analysis of Nuclear Transfer Embryo Derived Mouse Embryonic Stem Cells. Part II: Gene regulation [PDF]

, 2012
In a mouse model nuclear transfer embryo-derived embryonic stem cell lines (ntESCs) of various genetic backgrounds and donor cell types were compared with reference ESCs and analyzed comprehensively at molecular level as a second part of a larger study ...
Julianna Kobolak, Geißler, S., Mamo, S., Horsch, Marion, Horsch, M., Andras Dinnyes, Geissler, Sandra, Mamo, Solomon, Marion Horsch, Kobolak, J., Beckers, Johannes, Solomon Mamo, Kobolak, Julianna, Dinnyes, Andras, Beckers, J., Johannes Beckers, Sandra Geißler, Dinnyes, A.   +17 more
core   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Fetal and obstetrics manifestations of mitochondrial diseases

Journal of Translational Medicine
During embryonic and neonatal development, mitochondria have essential effects on metabolic and energetic regulation, shaping cell fate decisions and leading to significant short- and long-term effects on embryonic and offspring health.
Alessia Adelizzi, Anastasia Giri, Alessia Di Donfrancesco, Simona Boito, Alessandro Prigione, Emanuela Bottani, Valentina Bollati, Valeria Tiranti, Nicola Persico, Dario Brunetti   +9 more
doaj   +1 more source

Functions of NOD-like receptors (NLRs) in human diseases

Frontiers in Immunology, 2013
Nucleotide-binding and oligomerization domain (NOD)-like receptors (NLRs) are highly conserved cytosolic pattern recognition receptors that perform critical functions in surveying the intracellular environment for the presence of infection, noxious ...
Yifei eZhong, Anna eKinio, Maya eSaleh
doaj   +1 more source