Results 131 to 140 of about 505,187 (298)

Glucocorticoids Alter Bone Microvascular Barrier via MAPK/Connexin43 Mechanisms

Advanced Healthcare Materials, Volume 14, Issue 7, March 14, 2025.
Osteoporosis induced by Glucocorticoids (GCs) is a common complication of long‐term GC use in patients with inflammatory and autoimmune conditions, often leading to an increased fracture risk. A 3D bicellular endo‐osteo microfluidic platform is developed to explore pathogenic mechanisms underlying GCs‐induced osteoporosis, highlighting a novel MAPK ...
Eun‐Jin Lee, Peter Lialios, Micaila Curtis, James Williams IV, Yoontae Kim, Paul Salipante, Steven Hudson, Mandy B. Esch, Moshe Levi, Joanna Kitlinska, Stella Alimperti   +10 more
wiley   +1 more source

Fucosylated chondroitin sulfate alleviates colonic barrier dysfunction in Parkinson’s disease via epithelial cell modulation and microecology restoration

Journal of Functional Foods
Gastrointestinal disturbances frequently precede motor dysfunction and the hallmark pathological features of Parkinson's disease (PD). Fucosylated chondroitin sulfate (fCS-Ib), a polysaccharide derived from the sea cucumber Isostichopus badionotus, has ...
Yingying Chen, Youyuan Zhuo, Shuo Wan, Yawen Li, Shiguo Chen, Guang Wang, Nian Wu   +6 more
doaj  

CHANGES IN pH OF ALBUMEN AND YOLK IN THE COURSE OF EMBRYONIC DEVELOPMENT UNDER NATURAL AND ARTIFICIAL INCUBATION

, 1929
Alexis L. Romanoff, Anastasia J. Romanoff   +1 more
openalex   +2 more sources

Studies on sex-organ development. The hormonal regulation of steroidogenesis and adenosine 3′:5′-cyclic monophosphate in embryonic-chick ovary [PDF]

, 1977
Christina T. Teng, C S Teng
openalex   +1 more source

Recent Applications of Mesoporous Silica Nanoparticles in Gene Therapy

Advanced Healthcare Materials, EarlyView.
The review summarizes the synthesis of mesoporous silica nanoparticles (MSNs) with modifiable surface properties, functionalization strategies, mechanism of therapeutic payload release, and current applications in gene therapy, focusing on their capabilities in the targeted delivery of therapeutic nucleic acids, CRISPR‐Cas systems, and other genetic ...
Tamanna Binte Huq, Punnya Anil Kumar Jeeja, Sudip Kumar Dam, Sabya Sachi Das, Juan L. Vivero‐Escoto   +4 more
wiley   +1 more source

CNTF and Nrf2 Are Coordinately Involved in Regulating Self-Renewal and Differentiation of Neural Stem Cell during Embryonic Development

iScience, 2019
Summary: There is high risk of fetal neurodevelopmental defects in pregestational diabetes mellitus (PGDM). However, the effective mechanism of hyperglycemia-induced neurodevelopmental negative effects, including neural stem cell self-renewal and ...
Zhen-Peng Si, Guang Wang, Sha-Sha Han, Ya Jin, Yu-Xuan Hu, Mei-Yao He, Beate Brand-Saberi, Xuesong Yang, Guo-Sheng Liu   +8 more
doaj  

Influence of Temperature on the Embryonic Development of the Carp

, 1933
Takaharu Yamamoto
openalex   +2 more sources

Morphometric‐Assisted Prediction of Developmental Toxicity Using Stem Cell‐Based Embryo Models in Microwells

Advanced Healthcare Materials, EarlyView.
This proof‐of‐concept study involves high‐throughput teratogenicity screening of compounds using XEn/EpiCs, a 3D stem cell‐based embryo model, within microwells. The term ‘morphotoxicity’ is introduced to complement traditional cytotoxicity assays through automated feature extraction and machine‐learning‐assisted classification of morphologies.
Vinidhra Shankar, Athanasia Zoi Pappa, Clemens van Blitterswijk, Erik Vrij, Stefan Giselbrecht   +4 more
wiley   +1 more source

In Regards to the Embryonic Development of the Metagonimus takahashii and M. yokogawai.

, 1940
Shosaku Kuyama
openalex   +2 more sources

Embryonic Pituitary Adrenal Axis, Behavior Development and Domestication in Birds [PDF]

, 1978
James Martín
openalex   +1 more source