Results 291 to 300 of about 1,153,497 (356)

Strawberry Notch 1 Acts as a Transcriptional Regulator Driving Oncogenic Programs in Liver Carcinogenesis

Advanced Science, EarlyView.
This study reports that SBNO1 protein is upregulated in several cancer entities. SBNO1 protein interacts with the basal transcription factor TFIID via TAF4, enabling its recruitment to transcription start sites and the modulation of target gene expression.
Sarah Fritzsche, Raisatun Nisa Sugiyanto, Kira Gür, Alina Krumme, Maxime Le Marois, Angelika Fraas, Aslihan Inal, Mario Huerta, Vanessa Henriques, Eva Eiteneuer, Thomas Albrecht, Alphonse Charbel, Michael T. Dill, Carsten Sticht, Carolina De La Torre, Stefan Pusch, Arianeb Mehrabi, Kai Breuhahn, Junfang Ji, Peter Schirmacher, Benjamin Goeppert, Stephanie Roessler   +21 more
wiley   +1 more source

Role of mitochondrial dynamics in mouse preimplantation embryonic development and its molecular mechanisms. [PDF]

Sci Rep
Sun X, Li Q, Chen B.
europepmc   +1 more source

NDST3‐Induced Epigenetic Reprogramming Reverses Neurodegeneration in Parkinson's Disease

Advanced Science, EarlyView.
NDST3‐mediated epigenetic reprogramming revitalizes neuronal circuits in the substantia nigra and striatum to halt dopaminergic neuron degeneration and restore motor function in Parkinson's disease models. This strategy promotes neuronal maintenance and functional recovery, highlighting NDST3's therapeutic potential in neurodegenerative disorders ...
Yujung Chang, Yongwoo Na, Hyeonjoo Im, Garam Yang, Seungseon Yang, Hyun Soo Shim, Chunggoo Kim, GyeungYun Kim, Hyeok Ju Park, Hee Young Kim, Seung Eun Lee, Wonwoong Lee, Yoon Ha, Sungho Park, Jieun Kim, Won‐Young Cho, Woong Sun, Jong‐Seo Kim, Junsang Yoo   +18 more
wiley   +1 more source

USP9X as a Candidate Mediator of Prenatal Aspirin‐Induced Ovarian Reserve Reduction in Offspring Mice

Advanced Science, EarlyView.
This study suggests that prenatal aspirin exposure is associated with reduced ovarian reserve in offspring, associated with HDAC1‐linked epigenetic downregulation of Usp9x as a candidate mechanism. These preclinical findings provide new insights into fetal‐origin ovarian disorders and contribute to the evidence base concerning aspirin's gestational ...
Yating Li, Caiyun Ge, Wai Yen Yim, Hui Feng, Tiancheng Wu, Lu Chen, Qiaohua Xiong, Shumin Pan, Mei Wang, Huijun Chen, Yuanzhen Zhang, Hui Wang   +11 more
wiley   +1 more source

Multifaceted role of T-box transcription factor 4: From embryonic development to disease pathogenesis. [PDF]

Genes Dis
Yi L, Zhou L, Shao B, Xiang T, Tang J.
europepmc   +1 more source

Elevating Testosterone and Androstenedione Produces Temporary Sex-Dependent Variation in Japanese Quail (Coturnix japonica) Embryonic Development. [PDF]

J Exp Zool A Ecol Integr Physiol
Winnicki SK, Hauber ME, Paitz RT, Schelsky WM, Benson TJ.   +4 more
europepmc   +1 more source

Dynamic forces drive cell and organ morphology changes during embryonic development. [PDF]

Proc Natl Acad Sci U S A
Manna RK, Retzlaff EM, Hinman AM, Lan Y, Abdel-Razek O, Bates M, Hehnly H, Amack JD, Manning ML.   +8 more
europepmc   +1 more source

Sperm derived H2AK119ub1 is required for embryonic development in Xenopus laevis. [PDF]

Nat Commun
Francois-Campion V, Berger F, Oikawa M, Goumeidane M, Mouniée N, Chenouard V, Petrova K, Abreu JG, Fourgeux C, Poschmann J, Peshkin L, Gibeaux R, Jullien J.   +12 more
europepmc   +1 more source

Human amniotic mesenchymal stem cell-derived extracellular vesicles improve oocyte quality and embryonic development by increasing antioxidant capacity in aged mice. [PDF]

J Ovarian Res
La B, Jiang C, He J, Ni M, Zhou J, Wu H, Ning S, Dai W, Yan Z, Cui Y, Qin L, Liu J.   +11 more
europepmc   +1 more source