Results 131 to 140 of about 117,449 (268)

Three Decades of Enamel Matrix Derivative: From Dental Innovation to Extra-Oral Applications. [PDF]

Int J Dent
Mercado F, Loch C, Mustafa A, Lee E, Hecker M.   +4 more
europepmc   +1 more source

Peripheral κ opioid receptor in pain and inflammation: From molecular signalling and gene expression to drug discovery

British Journal of Pharmacology, EarlyView.
The κ opioid receptor (κ receptor, KOR) is a G protein‐coupled receptor with well established roles in analgesia and immune modulation. Although historically studied primarily in the central nervous system (CNS), growing evidence indicates that κ signalling in peripheral tissues plays an important role in regulating pain, inflammation and immune ...
Rumsha Khan, Elena C. A. Becker, Boglarka B. Bata, Christian W. Gruber   +3 more
wiley   +1 more source

CD19 CAR T cells for B-ALL with EMD. [PDF]

Blood Adv
Llaurador Caraballo G, Steffin D.
europepmc   +1 more source

Decreased Expression of FAT4 Promotes Multiple Myeloma Proliferation and Migration by Targeting the Hippo/YAP Pathway

Cancer Science, EarlyView.
This study provides the first comprehensive characterization of the functional impact, and mechanistic role of FAT4 in MM. Our findings highlight the tumor‐suppressive role of FAT4 in MM and uncover a novel mechanism by which FAT4 regulates the Hippo/YAP pathway.
Lina Zhang, Na Shen, Xin Cheng, Qinglin Shi, Lijuan Chen, Xuxing Shen   +5 more
wiley   +1 more source

CRLF2 rearrangement and extramedullary disease in B-cell acute lymphoblastic leukemia: a possible link? [PDF]

Blood Adv
Gava F, Yates B, Sun Z, Li G, O'Koren C, Adhikari B, Lugar S, Shalabi H, Mattison R, Turkbey EB, Yuan CM, Paietta E, Wang HW, Mullighan C, Silbert SK, Litzow M, Shah NN.   +16 more
europepmc   +1 more source

Oncogenic BRAF and KRAS Promote Global DNA Hypomethylation Through a Directed Pathway That Upregulates TET3

Cancer Science, EarlyView.
Oncogenic BRAF and KRAS promote global DNA hypomethylation through a directed pathway that increases the levels of TET3, which helps drive tumorigenesis. ABSTRACT Aberrant epigenetic modification is one of the characteristics of the cancer genome.
Ichiro Onoyama, W. Rod Hardy, Shoichiro Takeishi, Lihua Julie Zhu, Yanglan Tan, Lloyd Hutchinson, Jianhong Ou, Leyuan Ma, Ching‐Man Virbasius, Masafumi Yasunaga, Keiichi I. Nakayama, Scott A. Shaffer, Michael R. Green   +12 more
wiley   +1 more source

Native AMPA receptor architecture reveals SynDIG4 engagement and auxiliary subunit heterogeneity. [PDF]

Sci Adv
Fang C, Gouaux E.
europepmc   +1 more source

KPNA2 Drives Immunosuppression in Ovarian Cancer via CCL2/CCR2‐Dependent MDSC Recruitment

Cancer Science, EarlyView.
KPNA2 drives intratumoral MDSC accumulation and immunosuppression in ovarian cancer via the NF‐κB/CCL2/CCR2 axis. Mechanistically, KPNA2 facilitates NF‐κB/p65 nuclear translocation and induces CCL2 transcription, recruiting MDSCs to establish an immunosuppressive microenvironment.
Qingli Li, Jitong Zhao, Lu Yang, Lin Li, Ce Bian, Tao Yi, Huiqiong Huang, Gang Zheng, Xiaojuan Lin   +8 more
wiley   +1 more source

MSLN expression predicts a high risk of EMD in AML by promoting cell adhesion and metastasis via interaction with MUC16. [PDF]

Blood Adv
Wang L, Zhan Q, Luo J, Li J, He C, Zhu Y, Pei C, Chen Y, Tang NN, Yin J, Su L, Chen J, Xie M, Liu L, Luo XH.   +14 more
europepmc   +1 more source

Escalas multidimensionales (EMD)

, 2001
Las escalas multidimensionales (EMD o MDS si se sigue las siglas de su denominación en inglés) engloban a una gran variedad de técnicas multivariables cuya finalidad es obtener la estructura (factores o dimensiones) de los individuos (o variables) subyacente a una matriz de datos empíricos, lo que se consigue al representar dicha estructura en una ...
Rodríguez-Jaume, María-José, Mora Catalá, Rafael   +1 more
openaire   +1 more source