Results 41 to 50 of about 205,040 (276)

Gravitating BIon and BIon black hole with dilaton [PDF]

open access: yes, 2000
We construct static and spherically symmetric particle-like and black hole solutions with magnetic or electric charge in the Einstein-Born-Infeld-dilaton system, which is a generalization of the Einstein-Maxwell-dilaton (EMD) system and of the Einstein ...
Tamaki, Takashi, Torii, Takashi
core   +2 more sources

Temporal and spatial adaptation of transient responses to local features

open access: yesFrontiers in Neural Circuits, 2012
Interpreting visual motion within the natural environment is a challenging task, particularly considering that natural scenes vary enormously in brightness, contrast and spatial structure.
David C O'Carroll   +3 more
doaj   +1 more source

Pharmacometric modeling and machine learning analyses of prognostic and predictive factors in the JAVELIN Gastric 100 phase III trial of avelumab

open access: yesCPT: Pharmacometrics & Systems Pharmacology, 2022
Avelumab (anti–PD‐L1) is an approved anticancer treatment for several indications. The JAVELIN Gastric 100 phase III trial did not meet its primary objective of demonstrating superior overall survival (OS) with avelumab maintenance versus continued ...
Nadia Terranova   +11 more
doaj   +1 more source

Parallel Algorithms for Geometric Graph Problems [PDF]

open access: yes, 2014
We give algorithms for geometric graph problems in the modern parallel models inspired by MapReduce. For example, for the Minimum Spanning Tree (MST) problem over a set of points in the two-dimensional space, our algorithm computes a $(1+\epsilon ...
Andoni, Alexandr   +3 more
core   +1 more source

Analyse des signaux AM-FM basée sur une version B-splines de l'EMD-ESA [PDF]

open access: yes, 2012
In this paper a signal analysis framework for estimating time-varying amplitude and frequency functions of multicomponent amplitude and frequency modulated (AM–FM) signals is introduced.
BOUCHIKHI, Abdelkhalek   +1 more
core   +3 more sources

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Disease trajectory of SLE clinical endpoints and covariates affecting disease severity and probability of response: Analysis of pooled patient‐level placebo (Standard‐of‐Care) data to enable model‐informed drug development

open access: yesCPT: Pharmacometrics & Systems Pharmacology, 2023
Systemic lupus erythematosus (SLE) is an autoimmune disease affecting multiple organ systems. Many investigational agents have failed or shown only modest effects when added to standard of care (SoC) therapy in placebo‐controlled trials, and only two ...
Kosalaram Goteti   +14 more
doaj   +1 more source

Empirical mode decomposition-based facial pose estimation inside video sequences [PDF]

open access: yes, 2010
We describe a new pose-estimation algorithm via integration of the strength in both empirical mode decomposition (EMD) and mutual information. While mutual information is exploited to measure the similarity between facial images to estimate poses, EMD is
Jiang, Jianmin   +2 more
core   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Home - About - Disclaimer - Privacy