Results 31 to 40 of about 117,694 (268)
Journal of Analytical Methods in Chemistry, 2014 Biological samples present a range of complexities from homogeneous purified protein to multicomponent mixtures. Accurate qualification of such samples is paramount to downstream applications.
Ivona Strug +9 more
doaj +1 more source
Journal of Chromatography OpenThe application of frontal chromatography with cation exchange (CEX) resins to the downstream polishing of therapeutic monoclonal antibodies (mAbs) enables the selective removal of impurities, such as mAb aggregates and host cell proteins, with very high
Amit K. Dutta +8 more
doaj +1 more source
On the Memory Cost of EMD Algorithm
IEEE Access, 2022 Empirical mode decomposition (EMD) and its variants are adaptive algorithms that decompose a time series into a few oscillation components called intrinsic mode functions (IMFs). They are powerful signal processing tools and have been successfully applied in many applications.
Hsu-Wen Vincent Young +2 more
openaire +2 more sources
Temporal and spatial adaptation of transient responses to local features
Frontiers in Neural Circuits, 2012 Interpreting visual motion within the natural environment is a challenging task, particularly considering that natural scenes vary enormously in brightness, contrast and spatial structure.
David C O'Carroll +3 more
doaj +1 more source
CPT: Pharmacometrics & Systems Pharmacology, 2022 Avelumab (anti–PD‐L1) is an approved anticancer treatment for several indications. The JAVELIN Gastric 100 phase III trial did not meet its primary objective of demonstrating superior overall survival (OS) with avelumab maintenance versus continued ...
Nadia Terranova +11 more
doaj +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT We report a retrospective single‐center analysis of pediatric patients with relapsed or refractory B‐cell precursor acute lymphoblastic leukemia focusing on relapses outside of the typical locations, bone marrow, central nervous system, or testes.
Johanna Kunz +7 more
wiley +1 more source
Digital Signal Processing, 2020 Abstract In this paper an audio coding scheme based on the empirical mode decomposition in association with a psychoacoustic model is presented. The principle of the method consists in breaking down adaptively the audio signal into intrinsic oscillatory components, called Intrinsic Mode Functions (IMFs), that are fully described by their local ...
Abdel-Ouahab Boudraa +4 more
openaire +4 more sources
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
YIPFα1A expression is regulated by multilayered molecular mechanisms
FEBS Open Bio, EarlyView.YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji +2 more
wiley +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background and Objectives Multiple sclerosis (MS) exhibits racially disparate rates of disease progression. Black people with MS (B‐PwMS) experience a more severe disease course than non‐Hispanic White people with MS (NHW‐PwMS). Here we investigated structural and functional connectivity as well as structure–function decoupling in the ...
Emilio Cipriano +11 more
wiley +1 more source