Results 61 to 70 of about 115,954 (269)

Application of EMD and 1.5-dimensional spectrum in fault feature extraction of rolling bearing

open access: yesThe Journal of Engineering, 2019
The original signal of rolling bearing fault contains a large number of phase coupling components and is easily submerged in the background noise, which make the fault information difficult to be extracted accurately.
Zhanglei Jiang   +5 more
doaj   +1 more source

T Cell Exhaustion in Cancer Immunotherapy: Heterogeneity, Mechanisms, and Therapeutic Opportunities

open access: yesAdvanced Science, EarlyView.
T cell exhaustion limits immunotherapy efficacy. This article delineates its progression from stem‐like to terminally exhausted states, governed by persistent antigen, transcription factors, epigenetics, and metabolism. It maps the exhaustion landscape in the TME and proposes integrated reversal strategies, providing a translational roadmap to overcome
Yang Yu   +7 more
wiley   +1 more source

Tracking error analysis method of digital pulse power supply for heavy ion accelerator based on emd reconstruction

open access: yesMetrology and Measurement Systems, 2020
Assessment of the state of a pulse power supply requires effective and accurate methods to measure and reconstruct the tracking error. This paper proposes a tracking error measurement method for a digital pulse power supply.
Rongkun Wang, Sigun Sun, Bingtao Hu
doaj   +1 more source

Sustainable Materials Design With Multi‐Modal Artificial Intelligence

open access: yesAdvanced Science, EarlyView.
Critical mineral scarcity, high embodied carbon, and persistent pollution from materials processing intensify the need for sustainable materials design. This review frames the problem as multi‐objective optimization under heterogeneous, high‐dimensional evidence and highlights multi‐modal AI as an enabling pathway.
Tianyi Xu   +8 more
wiley   +1 more source

Remote Magnetomechanical Neuromodulation Uncovers Therapeutic Mechanisms for Alleviating Parkinsonian Symptoms in Freely Moving Mice

open access: yesAdvanced Science, EarlyView.
Magnetomechanical neuromodulation using magnetic nanodiscs enables remote activation of neurons. In a hemiparkinsonian mouse model, alternating magnetic fields actuate the nanodiscs to generate torque that opens mechanosensitive ion channels within the subthalamic nucleus, thereby modulating basal ganglia motor circuitry.
Anouk Wolters   +12 more
wiley   +1 more source

Valve Leakage Mode Recognition Method Based on Empirical Mode Decomposition and Random Forest

open access: yesYuanzineng kexue jishu
As a critical equipment in nuclear power plants, valve leakage would have an impact on system safety and stable operation. Using acoustic emission technology to identify valve leakage and distinguish between different leakage modes of internal and ...
ZHE Na1, ,  LIU Shiwen1, 2,  HE Pan1,  ZHENG Hua1,  WANG Liangzi1
doaj   +1 more source

Solid Ethanol as a Renewable, Low‐Toxicity, Electron‐Beam Direct Write, and Biomedical Material

open access: yesAdvanced Science, EarlyView.
3D ice lithography (3DIL) enables the fabrication of intricate submicrometer objects using ethanol as a renewable starting material. This study combines process optimization, structural and material analysis, and biomedical applications, from cell culture scaffolds to the patterning of neurostimulation electrodes, demonstrating performance in both in ...
Bruno Perdigão   +16 more
wiley   +1 more source

NET‐DNA Activates the ANXA2/TMEM215/BiP Axis to Promote Mitophagy‐Mediated Anoikis Resistance in Endometriosis

open access: yesAdvanced Science, EarlyView.
NET‐DNA is enriched during early endometriotic lesion establishment and drives anoikis resistance by promoting an ANXA2–TMEM215–BiP axis. This pathway strengthens ER–mitochondria contacts, enhances PINK1/Parkin‐associated mitophagy, preserves mitochondrial homeostasis, and supports ectopic stromal cell survival, thereby facilitating lesion persistence ...
Honglin Wang   +12 more
wiley   +1 more source

GLS1 Orchestrates Exosome‐Mediated Tumor‐Endothelial Communication to Facilitate Angiogenesis

open access: yesAdvanced Science, EarlyView.
This study reveals a previously unappreciated, non‐metabolic function of GLS1 in the control of tumor angiogenesis via exosome‐mediated CAV1‐TNC signaling, indicating that therapeutic targeting of GLS1 may offer a dual benefit by simultaneously suppressing tumor metabolic activity and angiogenic processes in head and neck cancer. ABSTRACT Glutaminase 1
Jianqiang Yang   +9 more
wiley   +1 more source

A Study Concerning Soft Computing Approaches for Stock Price Forecasting

open access: yesAxioms, 2019
Financial time-series are well known for their non-linearity and non-stationarity nature. The application of conventional econometric models in prediction can incur significant errors.
Chao Shi, Xiaosheng Zhuang
doaj   +1 more source

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