Results 81 to 90 of about 137,339 (254)

A Study Concerning Soft Computing Approaches for Stock Price Forecasting

open access: yesAxioms, 2019
Financial time-series are well known for their non-linearity and non-stationarity nature. The application of conventional econometric models in prediction can incur significant errors.
Chao Shi, Xiaosheng Zhuang
doaj   +1 more source

Transform Domain Based Iris Recognition using EMD and FFT [PDF]

open access: yes, 2017
Iris is one of the physiological trait which is used to identify the individuals. In this paper Transform Domain Based Iris Recognition using EMD and FFT is proposed.
Raja, K.B.   +3 more
core  

Distinct Cleavage Trajectories Mediated by DNA and RNA Substrate in Argonaute From Methanocaldococcus Fervens

open access: yesAdvanced Science, EarlyView.
This study characterizes MfAgo, an enzyme exhibiting highly efficient DNA‐guided DNA and RNA cleavage capability. Precise RNA cleavage strictly requires dimerization to stabilize the PIWI‐loop region, while its robust DNA cleavage functions in a dimerization‐independent manner.
Fuyong Huang   +9 more
wiley   +1 more source

Characterization of Full‐Length Antibody Complexes Through HDX‐Mass Spectrometry Coupled With NMR Spectroscopy: New Insight Into Avelumab/PD‐L1 Interaction

open access: yesAngewandte Chemie, EarlyView.
Combining HDX‐MS and NMR enables the mapping of epitopes and paratopes in full‐length antibody complexes, revealing transient interactions and potential artifacts. ABSTRACT Recombinant biomacromolecules have significantly transformed pharmaceuticals, in particular monoclonal antibodies (mAbs) that target key areas in oncology, immunology, inflammation,
Francesca Sacco   +13 more
wiley   +2 more sources

Similarity Continua and Criteria in Memetic Theory and Analysis [PDF]

open access: yes, 2014
The aim of this article is to schematize and quantify certain of the similarity relationships which are relevant to the application of memetics to music, in order to sketch a methodology by which evolutionarily significant resemblances (particularly in ...
Jan, Steven
core  

Mapping Embryonic Mouse Lung Development Using Enhanced Spatial Transcriptomics

open access: yesAdvanced Science, EarlyView.
The mammalian lung contains ∼50 cell types arranged along the airway epithelium. Here, deterministic barcoding sequencing (DBiT‐seq) is optimized to nearly double transcript recovery, enabling highly sensitive spatial mapping of the embryonic mouse lung.
Pengfei Zhang   +5 more
wiley   +1 more source

Molecular Basis for Activation to Inhibition Switching in Kv7.2 Channel Modulators

open access: yesAngewandte Chemie, EarlyView.
The paper describes the serendipitous discovery of chemical manipulation allowing the activator‐to‐inhibitor switching in Kv7.2 channel modulators. The molecular determinants driving this switch have been rationalized by multidisciplinary investigation encompassing synthetic and analytical chemistry, in silico methods, cryo‐EM analysis ...
Tania Ciaglia   +20 more
wiley   +2 more sources

Fault Diagnosis of Wind Turbine Double-Fed Induction Generator Based on Multi-Level Fusion and Measurement of Back-to-Back Converter Current Signal

open access: yesIranian Journal of Electrical and Electronic Engineering, 2022
One of the major faults in Doubly-Fed Induction Generator (DFIG) is the Inter-Turn Short Circuit (ITSC) fault. This fault leads to an asymmetry between phases and causes problems to the normal state between current lines.
M. Kamarzarrin   +3 more
doaj  

Facilitation of dragonfly target-detecting neurons by slow moving features on continuous paths

open access: yesFrontiers in Neural Circuits, 2012
Dragonflies detect and pursue targets such as other insects for feeding and conspecific interaction. They have a class of neurons highly specialised for this task in their lobula, the ‘small target motion detecting’ (STMD) neurons.
James R Dunbier   +3 more
doaj   +1 more source

Collagen‐Binding IL‐15 Immunocytokine Armed Oncolytic Adenovirus Establishes a Self‐Reinforcing Immunostimulatory Milieu to Potentiate Antitumor Immunity

open access: yesAdvanced Science, EarlyView.
Repurposing the dense tumor stroma from a physical barrier into an anchoring scaffold, an engineered oncolytic adenovirus encoding IL15C‐CBD overcomes the immunosuppressive microenvironment in triple‐negative breast cancer. Intratumoral viral replication secretes this collagen‐anchored immunocytokine, forming a localized cytokine depot.
Yaqi Yang   +14 more
wiley   +1 more source

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