Results 81 to 90 of about 117,449 (268)

Valve Leakage Mode Recognition Method Based on Empirical Mode Decomposition and Random Forest

Yuanzineng kexue jishu
As a critical equipment in nuclear power plants, valve leakage would have an impact on system safety and stable operation. Using acoustic emission technology to identify valve leakage and distinguish between different leakage modes of internal and ...
ZHE Na1, ,  LIU Shiwen1, 2,  HE Pan1,  ZHENG Hua1,  WANG Liangzi1
doaj   +1 more source

Radiation‐Induced Tumor‐Intrinsic LTβR N‐Glycosylation Suppresses Pyroptosis Through TRIM28‐Mediated PCBP2 SUMOylation to Promote Gastric Cancer Radioresistance

Advanced Science, EarlyView.
Radiotherapy triggers LTβR N‐glycosylation, enhancing its overall protein stability and nuclear retention. This accumulation drives TRIM28‐mediated PCBP2 SUMOylation, suppressing pyroptosis and conferring gastric cancer radioresistance. Therapeutically, a targeted nanoplatform (cRGD‐Lipo@EMD) effectively disrupts this regulatory axis, offering a highly
Weijie Zang, Yunlong Ji, Chunwang Zhou, Xiwen Li, Zhuang Lu, Guangze Zhang, Yu Chen, Wanjiang Xue, Yilin Hu   +8 more
wiley   +1 more source

A Study Concerning Soft Computing Approaches for Stock Price Forecasting

Axioms, 2019
Financial time-series are well known for their non-linearity and non-stationarity nature. The application of conventional econometric models in prediction can incur significant errors.
Chao Shi, Xiaosheng Zhuang
doaj   +1 more source

Lactate‐Driven Restriction of Mitochondrial Permeability Transition Promotes Resistance to Chemo‐Immunotherapy by Suppressing Tumor PANoptosis

Advanced Science, EarlyView.
Tumor‐derived lactate establishes a metabolic lock that drives chemo‐immunotherapy resistance by suppressing PANoptosis. Mechanistically, KAT8 lactylates the mitochondrial translocator ANT2, which recruits PGAM5 to dephosphorylate CypD. This cascade restricts mitochondrial permeability transition pore opening, preventing pro‐inflammatory mtDNA leakage.
Sen Zhong, Wenlong Chen, Fanglong Liu, Shengyi Zhou, Bolin Yu, Yuying Wang, Xiqian Zhou, Xuehui Wang, Diya Liu, Zhuoyu Zhang, Xinran Wang, Mounia Lalouly, Yiwen Li, Zhefei Du, Tao Yan, Zhihui Xiao, Zhou Zhou, Huanhuan Zhu, Fengyuan Qian, Bowen Zheng, Lin Fang   +20 more
wiley   +1 more source

An Attention‐Assisted Machine Learning System for Deep Microorganism Image Classification

Advanced Intelligent Systems, EarlyView.
An attention‐assisted DenseNet201 framework was developed for the classification of eight microorganism classes from microscopic images. The proposed model improved classification performance and achieved an accuracy of 87.38%. Advances in microbiology and environmental health fundamentally depend on precise and timely microorganism identification ...
Yujie Li, Ailing Gao, Guoxu Liu, Chunlei Chen, Yonghui Zhang, Sunkyoung Kang, M. Khosravi   +6 more
wiley   +1 more source

Fault Diagnosis of Wind Turbine Double-Fed Induction Generator Based on Multi-Level Fusion and Measurement of Back-to-Back Converter Current Signal

Iranian Journal of Electrical and Electronic Engineering, 2022
One of the major faults in Doubly-Fed Induction Generator (DFIG) is the Inter-Turn Short Circuit (ITSC) fault. This fault leads to an asymmetry between phases and causes problems to the normal state between current lines.
M. Kamarzarrin, M. H. Refan, P. Amiri, A. Dameshghi   +3 more
doaj  

Facilitation of dragonfly target-detecting neurons by slow moving features on continuous paths

Frontiers in Neural Circuits, 2012
Dragonflies detect and pursue targets such as other insects for feeding and conspecific interaction. They have a class of neurons highly specialised for this task in their lobula, the ‘small target motion detecting’ (STMD) neurons.
James R Dunbier, Steven D Wiederman, Patrick A Shoemaker, David C O'Carroll   +3 more
doaj   +1 more source

Clock Genes Regulate Ca2+ Signaling and Mitochondrial Bioenergetics to Inhibit Sjögren Disease

Arthritis &Rheumatology, EarlyView.
Objective Although Ca2+ signaling and metabolism have been identified as key determinants for the development of Sjögren disease (SjD), the intricate connection between them and salivary gland physiology remains poorly understood. Methods Fluorescence‐based Ca2+ imaging, RNA sequencing, and mitochondrial activity were used to investigate the effects of
Viktor R. Drel, Manigandan Venkatesan, Rahul S. Jasrotia, Yuyang Sun, Viviane Nascimento da Conceicao, Neelanjan Vishnu, Shankara N. Varadarajan, Venugopal R. Bovilla, Rajender K. Motiani, Shobhan Gaddameedhi, Bibhuti B. Mishra, Muniswamy Madesh, Brij B. Singh   +12 more
wiley   +1 more source

Evaluating and leveraging large language models in clinical pharmacology and therapeutics assessment: From exam takers to exam shapers

British Journal of Clinical Pharmacology, EarlyView.
Aims In medical education, the ability of large language models (LLMs) to match human performance raises questions about their potential as educational tools. This study evaluates LLMs' performance on Clinical Pharmacology and Therapeutics (CPT) exams, comparing their results to medical students and exploring their ability to identify poorly formulated
Alexandre O. Gérard, Diane Merino, Marc Labriffe, Fanny Rocher, Delphine Viard, Laurence Zemori, Thibaud Lavrut, Erik M. Donker, Joost D. Piët, Jean‐Paul Fournier, Milou‐Daniel Drici, Alexandre Destere   +11 more
wiley   +1 more source

Trends in the utilization, expenditure and costs of noninsulin glucose‐lowering drugs in the Medicaid population: Steady increases in glucagon‐like peptide‐1 receptor agonist and sodium–glucose transporter‐2 inhibitor use, prices and expenditure

British Journal of Clinical Pharmacology, EarlyView.
Aims This study aimed to analyse changes in the utilization, expenditure and average cost of noninsulin glucose‐lowering drugs (GLDs) between 2008 and 2023. Methods This was a retrospective observational study of 2008–2023 data from the National Medicaid State Drug Utilization database.
Rawan O. Almadfaa
wiley   +1 more source