Results 61 to 70 of about 1,922,072 (410)

Emergence.

open access: yesPhilosophica, 1997
Abstract ‘Emergence’ looks at the relations between building blocks, generated systems, and the phenomenon of emergence. To understand emergent phenomena, it is necessary to describe the emergence of a system’s behaviour from the non-additive interactions of its building blocks. Emergence occurs when the generators for a generated system
openaire   +1 more source

Feasibility of a ctDNA multigenic panel for non‐small‐cell lung cancer early detection and disease surveillance

open access: yesMolecular Oncology, EarlyView.
Plasma‐based detection of actionable mutations is a promising approach in lung cancer management. Analysis of ctDNA with a multigene NGS panel identified TP53, KRAS, and EGFR as the most frequently altered, with TP53 and KRAS in treatment‐naïve patients and TP53 and EGFR in previously treated patients.
Giovanna Maria Stanfoca Casagrande   +11 more
wiley   +1 more source

What School Principals Need to Know About Curriculum and Instruction [PDF]

open access: yes, 2001
Looks at what school leaders need to know about instructional practices, organizing a school for greater student learning, supporting teacher development, and balancing school improvement with non-instructional issues and ...
Gene Bottoms
core  

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

open access: yesMolecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto   +13 more
wiley   +1 more source

Policy implementation challenges and the ritualization of public health emergency plans: An investigation of urban communities in Jiangsu Province, China

open access: yesFrontiers in Public Health, 2023
IntroductionThe COVID-19 pandemic has been a global public health emergency, and countries worldwide have responded to it through a vast array of pre-planned, adaptively devised and ad-hoc measures.
Rui Zhang   +3 more
doaj   +1 more source

Working as an EMT [PDF]

open access: yes, 2010
The work of Emergency Medical Technicians (EMTs) is often the difference between life and death for a patient. EMTs respond to various medical emergencies including car accidents, heart attacks, slips and falls of the elderly, childbirth, and gunshot ...
Mietlicki, Robert
core   +1 more source

Emerging Options for Emergency Contraception [PDF]

open access: yesClinical Medicine Insights: Reproductive Health, 2013
Emergency post-coital contraception (EC) is an effective method of preventing pregnancy when used appropriately. EC has been available since the 1970s, and its availability and use have become widespread. Options for EC are broad and include the copper intrauterine device (IUD) and emergency contraceptive pills such as levonorgestrel, ulipristal ...
Atsuko Koyama   +2 more
openaire   +4 more sources

In-Flight Medical Emergencies: A Review

open access: yesJournal of the American Medical Association (JAMA), 2018
Importance In-flight medical emergencies (IMEs) are common and occur in a complex environment with limited medical resources. Health care personnel are often asked to assist affected passengers and the flight team, and many have limited experience in ...
C. Martin-Gill, T. Doyle, D. Yealy
semanticscholar   +1 more source

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

open access: yesMolecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués   +3 more
wiley   +1 more source

СONSTRUCTION AND THE ALGORITHM OPERATION OF THE LASER COMBINED FIRE DETECTOR

open access: yesПриборы и методы измерений, 2017
The point optical smoke detector is currently the most effective means of fire detection at the early stage of its occurrence. The urgent task for this type of detector is to increase its sensitivity to «black» smoke and ensure resilience to the effects ...
A. I. Kitsak   +6 more
doaj   +1 more source

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