Results 81 to 90 of about 1,922,072 (410)
International Journal of Modern Physics A, 2003 A possible resolution of the incompatibility of quantum mechanics and general relativity is that the relativity principle is emergent. I show that the central paradox of black holes also occurs at a liquid-vapor critical surface of a bose condensate but is resolved there by the phenomenon of quantum criticality.
openaire +3 more sources
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
Diagnosis and Management of Oncologic Emergencies
Western Journal of Emergency Medicine, 2019 Oncologic emergencies may be seen in any emergency department and will become more frequent as our population ages and more patients receive chemotherapy.
Sarah Klemencic, J. Perkins
semanticscholar +1 more source
Molecular Oncology, EarlyView.The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source
BMC Health Services ResearchBackground First responders, when arriving at a disaster, need a rapid analysis of the environment in which they are going to operate, as they have to assess the conditions surrounding potential victims and neutralize any risks that may exist.The EU ...
Ana María Cintora-Sanz +5 more
doaj +1 more source
Ready or Not? Protecting the Public's Health in the Age of Bioterrorism, 2004 [PDF]
, 2004 Examines ten key indicators to evaluate state preparedness to respond to bioterrorist attacks and other public health emergencies.
Laura M. Segal +3 more
core
Psychology, Health & Medicine, 2017 Little is known about the patterns and mechanisms by which humanitarian emergencies may exacerbate violence against children. In this article, we propose using the ecological framework to examine the impact of humanitarian emergencies on interpersonal ...
Beth L Rubenstein, L. Stark
semanticscholar +1 more source
Molecular Oncology, EarlyView.We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source
Ready or Not? Protecting the Public's Health From Diseases, Disasters, and Bioterrorism, 2008 [PDF]
, 2008 Examines ten indicators to assess progress in state readiness to respond to bioterrorism and other public health emergencies. Evaluates the federal government's and hospitals' preparedness.
Jeffrey Levi +3 more
core +1 more source
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source