Results 41 to 50 of about 26,824 (263)

Arginine methylation as a regulatory ratchet in cancer: From substrate selection to malignant‐state stabilization

open access: yesMolecular Oncology, EarlyView.
Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley   +1 more source

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

open access: yesMolecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez   +5 more
wiley   +1 more source

Design of integrated communication system of mine emergency rescue command

open access: yesGong-kuang zidonghua, 2016
Taking development trend of mine emergency rescue command communication system as design requirements, a design scheme of integrated communication system of mine emergency rescue command which combines with wired SHDSL, wireless WiFi and satellite ...
ZHENG Wanbo, WU Yanqing
doaj   +1 more source

Genetic dissection of human ABCE1 in yeast reveals separable requirements for ribosome recycling and suppression of aberrant reinitiation

open access: yesFEBS Open Bio, EarlyView.
Human ABCE1 cannot functionally replace its yeast ortholog. Yeast–human chimera analysis identified NBD1 as a major interspecies barrier. Genetic screening yielded hABCE1 revertants that rescue yeast viability but fail to suppress aberrant translation reinitiation in the 3′ UTR.
Eriko Nakata   +3 more
wiley   +1 more source

Acute liver failure induced by hepatitis E virus complicated with pancreatitis and refractory acute respiratory distress syndrome after rapid ascent to high altitude: a case report and literature review

open access: yesFrontiers in Physiology
BackgroundAcute respiratory distress syndrome (ARDS) and pancreatitis are fatal extrahepatic complication of hepatitis E virus (HEV)–induced acute liver failure (ALF).
Bowen Wang   +6 more
doaj   +1 more source

Recent insights into the molecular mechanism of ubiquinol oxidation by cytochrome bc1

open access: yesFEBS Open Bio, EarlyView.
The review reflects on the mechanism of the catalytic reaction in cytochrome bc1: the electron bifurcation that involves the separation of two electrons derived from the quinol oxidation to opposite sides of the enzyme across the membrane. This review summarizes the long‐standing effort to understand the mechanism of quinol oxidation catalyzed by ...
Anna Wójcik‐Augustyn   +2 more
wiley   +1 more source

Primary and Secondary Commandments in the Quran; Criteria and Examples [PDF]

open access: yesآموزه‌‌های فقه مدني, 2011
T here are two kinds of religious commandments: one is a command that is established for a thing as an action regardless of the states and knowledge and ignorance of the obligatee towards it like necessity of praying, fasting, and prohibition of ...
Dr. Reza Haghpanah
doaj  

Heuristics and operational research in emergency situations and civil defence education

open access: yesVojnotehnički Glasnik, 2014
This paper presents  problem solving using heuristics and operational research in order to make appropriate decisions in emergency situations with a particular emphasis on the application of a heuristic model of team training for emergency situations. It
Paun J. Bereš, Kristian P. Bereš
doaj   +1 more source

Self‐Regulated Learning Meets AI: Reinterpreting Self‐Regulation, Co‐Regulation, and Socially Shared Regulation in Human–AI Interaction

open access: yesNew Directions for Adult and Continuing Education, EarlyView.
ABSTRACT Advancing artificial intelligence (AI) has transformed learning and work, yet higher education and professional development programs have not systematically equipped learners for AI‐prevalent environments. This lack of preparation creates uncertainty regarding control, responsibility, trust, and accountability.
Moon‐Heum Cho, Jerusalem Merkebu
wiley   +1 more source

Psychological resilience among emergency medical teams in Singapore

open access: yesWestern Pacific Surveillance and Response
Problem: Emergency medical teams (EMTs) responding to mass casualty incidents attend to casualties in a chaotic, high-pressure and resource-limited environment that is vastly different from their day-to-day work. The nature of mass casualty incidents and
Eunice Chan   +6 more
doaj   +1 more source

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