Results 91 to 100 of about 11,132,232 (348)

Spatial biology in cancer epigenetics

open access: yesMolecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

Informed Consent Documentation for Lumbar Puncture in the Emergency Department

open access: yesWestern Journal of Emergency Medicine, 2014
Introduction: Informed consent is a required process for procedures performed in the emergency department (ED), though it is not clear how often or adequately it is obtained by emergency physicians.
Pankaj B. Patel   +3 more
doaj   +1 more source

Castration‐resistant prostate cancer cells are addicted to the high activity of cyclin‐dependent kinase 2

open access: yesMolecular Oncology, EarlyView.
We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee   +3 more
wiley   +1 more source

Depression Is Associated with Repeat Emergency Department Visits in Patients with Non-specific Abdominal Pain

open access: yesWestern Journal of Emergency Medicine, 2014
Introduction: Patients with abdominal pain often return multiple times despite no definitive diagnosis. Our objective was to determine if repeat emergency department (ED) use among patients with non-specific abdominal pain might be associated with a ...
Andrew Charles Meltzer   +2 more
doaj   +1 more source

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

open access: yesMolecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault   +12 more
wiley   +1 more source

Reducing attendances and waits in emergency departments : a systematic review of present innovations [PDF]

open access: yes, 2004
Reducing the waits in emergency departments is important for patients and is a government priority. In order to reduce waits the whole system must be considered.
McLeod, Eileen   +6 more
core  

Suicide Prevention in an Emergency Department Population: the ED-SAFE Study

open access: yesJAMA psychiatry, 2017
Importance Suicide is a leading cause of deaths in the United States. Although the emergency department (ED) is an opportune setting for initiating suicide prevention efforts, ED-initiated suicide prevention interventions remain underdeveloped. Objective
I. Miller   +10 more
semanticscholar   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

open access: yesFEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard   +12 more
wiley   +1 more source

Other title: Title from ODPS Ohio Emergency Management Agency newsletters home page: Ohio's emergency management news

open access: yes, 2008
Biweekly, May 25, 2007-Sept. 29, 2008.; Weekly, -May 11, 2007.; Electronic coverage as of Sept. 5, 2014: Vol. 3, no. 1 (Jan. 6, 2006)-v. 5, no. 17 (Sept. 29, 2008); "A publication of the Ohio Emergency Management Agency, a division of the Ohio Department
Ohio Emergency Management Agency.
core  

Emergency department patients' perception of care: do doctors understand their patients? [PDF]

open access: yes, 2011
Includes abstract.Includes bibliographical references (leaves 42-55).The aim of my study is to directly compare the patient’s perceptions of care received in the emergency department to that of the attending physician’s.
Mahomed, Zeyn
core   +1 more source

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