Results 81 to 90 of about 8,173,709 (257)

A retrospective analysis of time delays in patients presenting with stroke to an academic emergency department

South African Journal of Radiology, 2018
Background: Stroke presents commonly to the emergency department (ED), and is a common cause of morbidity and mortality in South Africa. Early ED presentation and early neuroimaging are required in order for thrombolysis to be a potential therapeutic ...
Diteboho Khalema, Lara N. Goldstein, Susan Lucas   +2 more
doaj   +1 more source

Adenosine triphosphate as a modulator of protein interactions and stability

FEBS Open Bio, EarlyView.
ATP is best known as the cell's energy currency, but it also shapes how proteins fold, interact, aggregate and form biomolecular condensates. This review explains the emerging physical principles behind these effects, including weak binding to charged protein regions, magnesium‐dependent behaviour and concentration‐dependent control of protein ...
Shuyuan Tan, Robin Curtis
wiley   +1 more source

Death in the emergency department: A rapid review

, 2021
Those who work in emergency departments rarely consider them a ‘good’ place to die. Recent New Zealand research suggests that palliative patients and their whānau/family – particularly those living in more deprived areas – can benefit from hospital ...
Anderson, NE
core  

De novo synthesis of short‐chain aldehydes and hydrocarbons secreted by the brown marmorated stink bug Halyomorpha halys

FEBS Open Bio, EarlyView.
The brown marmorated stink bug, Halyomorpha halys, mainly secretes 4‐oxo‐(E)‐2‐hexenal, (E)‐2‐decenal, dodecane and tridecane, a mixture representative of that released by many heteropterans. We demonstrated that H. halys can synthesise these secretory components de novo using dietary glucose.
Haruna Fujimori, Koji Noge
wiley   +1 more source

Australian hospital statistics 2012-13: emergency department care [PDF]

, 2013
Emergency department presentations increased by 4.0% on average each year between 2008-09 and 2012-13, this report finds.ow many emergency department presentations were there?

core  

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

FEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain, Elise Buret, Le Hoang Thanh Nguyen, Marion Cocheteux, Nicolas Touya, Mélanie Dhayer, Romain Dubois, Frank Lafont, Sebastien Janel, Patrice Maboudou, Steve Lancel, Philippe Marchetti   +11 more
wiley   +1 more source

Genetic dissection of human ABCE1 in yeast reveals separable requirements for ribosome recycling and suppression of aberrant reinitiation

FEBS Open Bio, EarlyView.
Human ABCE1 cannot functionally replace its yeast ortholog. Yeast–human chimera analysis identified NBD1 as a major interspecies barrier. Genetic screening yielded hABCE1 revertants that rescue yeast viability but fail to suppress aberrant translation reinitiation in the 3′ UTR.
Eriko Nakata, Yuxin Li, Kei Endo, Koichi Ito   +3 more
wiley   +1 more source

The association between vital signs and mortality in a retrospective cohort study of an unselected emergency department population [PDF]

, 2016
Background: Vital signs are widely used in emergency departments. Previous studies on the association between vital signs and mortality in emergency departments have been restricted to selected patient populations.
Martin Nordberg, Castren, Maaret, Kurland, Lisa,, Castrén, Maaret,, Lisa Kurland, Kurland, Lisa, Nordberg, M,, Nordberg, Martin,, Nordberg, Martin, Castren, M, Malin Ljunggren, Kurland, L,, Ljunggren, Malin, Maaret Castrén, Ljunggren, M,, Ljunggren, Malin,   +15 more
core   +1 more source

Recent insights into the molecular mechanism of ubiquinol oxidation by cytochrome bc1

FEBS Open Bio, EarlyView.
The review reflects on the mechanism of the catalytic reaction in cytochrome bc1: the electron bifurcation that involves the separation of two electrons derived from the quinol oxidation to opposite sides of the enzyme across the membrane. This review summarizes the long‐standing effort to understand the mechanism of quinol oxidation catalyzed by ...
Anna Wójcik‐Augustyn, Artur Osyczka, Marcin Sarewicz   +2 more
wiley   +1 more source

Advancing Patient‐centered Outcomes in Emergency Diagnostic Imaging: A Research Agenda

, 2015
Diagnostic imaging is integral to the evaluation of many emergency department (ED) patients. However, relatively little effort has been devoted to patient-centered outcomes research (PCOR) in emergency diagnostic imaging. This article provides background
LeBlanc, Annie, Kimberly E. Applegate, Vaughan, William, Judd E. Hollander, McCabe, Aileen M., Angela M. Mills, M. Fernanda Bellolio, Mills, Angela M., Hemal K. Kanzaria, Grudzen, Corita R., Bellolio, Fernanda, Zachary M. Meisel, Corita R. Grudzen, Annie LeBlanc, Christopher R. Carpenter, Aileen M. McCabe, Erik P. Hess, Lisa H. Merck, William Vaughan, Carpenter, Christopher R., Meisel, Zachary M., Merck, Lisa H., Hollander, Judd E., Jason T. Schaffer, Kanzaria, Hemal K., Schaffer, Jason T., Hess, Erik P., Applegate, Kimberly E.   +27 more
core   +1 more source