Results 61 to 70 of about 14,589,008 (193)

Type I interferons modulate autophagy to shape gemcitabine response in pancreatic cancer cells

FEBS Open Bio, EarlyView.
Type I interferons differentially modulate autophagy and the response of pancreatic cancer cells to gemcitabine. IFNα2b stimulates autophagic flux and protects cells from gemcitabine‐induced cell death, contributing to chemoresistance. In contrast, IFNβ1a inhibits autophagosome formation and enhances gemcitabine‐induced cell death, resulting in ...
Lucy E. Bonilla, Martín M. Ledesma, Santiago A. Behr, Matías A. Pibuel, María L. Palanek, Daniel H. Grasso, Maria N. Garcia, Juan Garona, Silvina L. Lompardía, Elida Álvarez, Daniela L. Papademetrio   +10 more
wiley   +1 more source

Variable-Gain Control Method for Grid-Forming Converters of Deloaded Wind Turbine Generator to Improve Short-Term Frequency Stability Following Generation Loss

IEEE Access
Conventional wind turbine generators (WTs) with grid-following converters (GFLs) lack inertial response, posing frequency stability challenges. By applying grid-forming converter (GFM) control, WTs can provide inertial response to support system ...
Seongheon Oh, Kenichi Kawabe
doaj   +1 more source

Current limitations of cryogenic microwave oscillator frequency stability

, 2014
Technical paperCryogenic microwave oscillators built upon sapphire loaded cavity resonators exhibit excellent levels of frequency stability. Here we present an overview of the current understanding of the various processes and noise sources that limit ...
Parker, S., John G. Hartnett, Stephen R. Parker, Ivanov, E., Tobar, M., Michael E. Tobar, Hartnett, J., Eugene N. Ivanov   +7 more
core   +1 more source

Dactolisib outperforms Rapamycin in potentiating apoptosis induced by XPO1, Bcl‐2 and Mcl‐1 blockade in preclinical glioblastoma models

FEBS Open Bio, EarlyView.
The PAM pathway and its impact on cellular metabolism. Color‐coded key symbols represent Rapamycin (R, orange, targeting mTOR) and Dactolisib (D, green, targeting PI3K/mTOR), indicating their sites of action. Created with BioRenders.com. Glioblastoma resists therapy through interconnected survival programs.
Kai Zhao, Leonie Meyer, Madita Braun, Katharina Otte, Celine Bitter, Maite Pawlik, Hartmann Raifer, Frederik Helmprobst, Axel Pagenstecher, Hans Urban, Michael C. Burger, Michael W. Ronellenfitsch, Joachim P. Steinbach, Jarmila Jedelská, Shamim Bagheri, Behrooz H. Yousefi, Pietro Di Fazio, Markus Luster, Andreas H. Mahnken, Andreas Neubauer, Andreas Burchert, Christopher Nimsky, Jörg W. Bartsch, Tillmann Rusch   +23 more
wiley   +1 more source

Emergency Load-Shedding Strategy for Power System Frequency Stability Based on Disturbance Location Identification

Energies
With the evolution of modern power systems, the proportion of renewable energy generation in the grid continues to grow. At the same time, grid operation modes have become increasingly complex and dynamic, leading to heightened uncertainty in disturbance
Zhenglong Sun, Rongbin Zhang, Rui Zhang, Chao Pan, Weihan Chen, Zewei Li   +5 more
doaj   +1 more source

Other title: Title from ODPS Ohio Emergency Management Agency newsletters home page: Ohio's emergency management news

, 2008
Biweekly, May 25, 2007-Sept. 29, 2008.; Weekly, -May 11, 2007.; Electronic coverage as of Sept. 5, 2014: Vol. 3, no. 1 (Jan. 6, 2006)-v. 5, no. 17 (Sept. 29, 2008); "A publication of the Ohio Emergency Management Agency, a division of the Ohio Department
Ohio Emergency Management Agency.
core  

Hydrogel platforms for 3D cardiac tissue engineering and fibrotic disease modelling

FEBS Open Bio, EarlyView.
Hydrogel‐based cardiac tissue models are advancing our understanding of heart health and disease. By incorporating electrical conductivity, aligned structures, and tunable mechanical properties, these platforms better replicate the complex environment of native heart tissue.
Harrison Porritt, Annika Winbo, Jenny Malmström   +2 more
wiley   +1 more source

Emergency Frequency Control Method for DC Island System Based on Dynamic Interaction Energy

Xiandai dianli
To address the issue of frequency instability caused by power imbalance when HVDC transmission system enters the island operation state, an emergency frequency control method based on dynamic interactive energy is proposed.
Liang WANG, Yuxin SHI, Guoming MA, Jing MA, Yufeng ZHAO, Bozong WANG, Zhongyao BAI   +6 more
doaj   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

Other title: Local Emergency Planning Committee Handbook

, 2014
application/pdf March 2014This handbook is designed for Local Emergency Planning Committees (LEPCs) in the State of Kansas. This handbook was developed to provide general guidance on LEPC duties, responsibilities and organization.;--Page 11.LEPC ...
Kansas. Division of Emergency Management.
core   +1 more source