Results 31 to 40 of about 4,140,192 (302)

Guidelines for reasonable and appropriate care in the emergency department (GRACE): Recurrent, low‐risk chest pain in the emergency department [PDF]

, 2021
This first Guideline for Reasonable and Appropriate Care in the Emergency Department (GRACE-1) from the Society for Academic Emergency Medicine is on the topic: Recurrent, Low-risk Chest Pain in the Emergency Department.
Stahl, John H., Diercks, Deborah B, Paul I. Musey, Kontos, Michael C., Gottlieb, Michael, Stopyra, Jason P, Hess, Erik P, Musey, Paul I, Mumma, Bryn E, Probst, Marc A., Musey, Paul I., Bellolio, Fernanda, Kontos, Michael C, Musey, Paul I., Jr., Michael Gottlieb, Christopher R. Carpenter, John H. Stahl, Jason P. Stopyra, Diercks, Deborah B., Mumma, Bryn E., Erik P. Hess, Jeffrey A. Kline, Fernanda Bellolio, Upadhye, Suneel, Stopyra, Jason P., Bryn E. Mumma, Chang, Anna Marie, Stahl, John H, Carpenter, Christopher R., Kline, Jeffrey A., Anna Marie Chang, Carpenter, Christopher R, Probst, Marc A, Suneel Upadhye, Deborah B. Diercks, Kline, Jeffrey A, Michael C. Kontos, Hess, Erik P., Marc A. Probst   +38 more
core   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Epigenetic reprogramming of lineage switching in cancer

FEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı, Burcu Akman, Ezgi Bağırsakçı, Nese Atabey, Serap Erkek‐Ozhan   +4 more
wiley   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

FEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk, Gailing Ma, Robin Antrobus, Diego Manni, Marco Trevisan‐Herraz, Mustafa Khwaja, Max Brown, Gavin D. Richardson, Masaaki Komatsu, Daniel Erskine, Viktor I. Korolchuk, Tetsushi Kataura   +11 more
wiley   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source

Emergency Medicine

World Journal of Advanced Research and Reviews
Emergency defines the potential provision of rapid and effective Medical Nursing Care, in situations where life is threatened. Emergency medicine is defined as the branch of Medicine that operates within an organized EMS. Emergency Medicine System (EMS) is defined as the organized set of provision of immediate pre-hospital, in-hospital and inter ...
openaire   +4 more sources

Hyperbaric medicine in emergencies

Vojnosanitetski pregled, 2008
<zakljucak> Imajuci u vidu mali broj kontraindikacija, primena HBOT od velike je koristi u zbrinjavanju urgentnih stanja, narocito u kombinaciji sa hirurskim i medikamentnim procedurama. .
Rabrenović Milorad, Matunović Radomir, Rabrenović Violeta, Todorović Veljko, Mićević Dušan, Zoranović Uroš   +5 more
openaire   +3 more sources

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Is Emergency Medicine the Right Choice for Me? [PDF]

, 2019
One of the hardest decisions a medical student has to make is the choice of specialty. Many studies have explored what influences the choice of emergency medicine (EM) as a specialty.
Schofer, Joel M., Asher, Shellie L., Rosen, Brett, Rosen, Peter L., Wald, David A., Kazzi, Amin Antoine Nabih, Cheaito, Mohamad Ali, Epter, Michael L.   +7 more
core   +1 more source