Results 61 to 70 of about 4,140,192 (302)

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

Procedures in emergency medicine: bag-valve-mask ventilation

, 2013
This video is part of a series of videos demonstrating common procedures performed in the Emergency Medicine setting. It was prepared by Cape Town Emergency Medicine's consultants and registrars. This short simulated video demonstrates the technique of "
Oosthuizen, Almero, Cape Town Emergency Medicine Registrars   +1 more
core   +1 more source

Spatial biology in cancer epigenetics

Molecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

Procedures in emergency medicine: nasopharyngeal airway insertion

, 2013
This video is part of a series of videos demonstrating common procedures performed in the Emergency Medicine setting. It was prepared by Cape Town Emergency Medicine's consultants and registrars.
Oosthuizen, Almero, Cape Town Emergency Medicine Registrars   +1 more
core  

Castration‐resistant prostate cancer cells are addicted to the high activity of cyclin‐dependent kinase 2

Molecular Oncology, EarlyView.
We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee, Alessia Marin, Shivani Yalala, Harri M. Itkonen   +3 more
wiley   +1 more source

Procedures in emergency medicine: insertion of intercostal drain

, 2013
This video forms part of a series of videos demonstrating common procedures performed in the Emergency Medicine setting. It was prepared by Cape Town Emergency Medicine's consultants and registrars.
Oosthuizen, Almero, Cape Town Emergency Medicine Registrars   +1 more
core   +1 more source

Arginine methylation as a regulatory ratchet in cancer: From substrate selection to malignant‐state stabilization

Molecular Oncology, EarlyView.
Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley   +1 more source

Procedures in emergency medicine: intraosseous access in a child

, 2013
This video is part of a series of videos demonstrating common procedures performed in the Emergency Medicine setting. It was prepared by Cape Town Emergency Medicine's consultants and registrars.
Oosthuizen, Almero, Cape Town Emergency Medicine Registrars   +1 more
core   +1 more source

Global emergency medicine: A scoping review of the literature from 2023

Objective: The Global Emergency Medicine Literature Review (GEMLR) highlights the highest-quality research addressing emergency care in resource-limited settings (ECRLS).
Broccoli, Morgan C., Lee, J. Austin, Kivlehan, Sean M., Strong, Jonathan M., Quao, Nana Serwaa A., de Oliveira Salvador, Gabriel Lucca, Hexom, Braden J., Collier, Amanda, Dawson-Amoah, Nanaba A., Dyal, Jonathan, Global Emergency Medicine Literature Review (GEMLR) Group, Kampalath, Vinay, Bandolin, N. Shakira, Bonney, Joseph, Rees, Chris A.   +14 more
core   +1 more source

Professionalism Milestones Assessments Used by Emergency Medicine Residency Programs: A Cross-sectional Survey. [PDF]

, 2019
INTRODUCTION: Professionalism is a vital component of quality patient care. While competency in professionalism is Accreditation Council for Graduate Medical Education (ACGME)-mandated, the methods used to evaluate professionalism are not standardized ...
Love, Jeffrey N., Domingues, R., Volz, Emilio G, Fernez-Frackelton, M., Volz, Emilio G., Stehman, Christine R, Soares, William, Fernández-Frackelton, Madonna, Volz, E.G., Soares, W., Stehman, C.R., Domingues, Rui, Hochman, S., Love, Jeffrey N, Stehman, Christine R., Soares, William B., Love, J.N., Hochman, Steven   +17 more
core   +1 more source