Results 41 to 50 of about 6,320,379 (300)
Translophagy—A potential link between autophagy impairment and translational errors
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
Emergence of response‐response relations [PDF]
AbstractThe present study examined whether bidirectional response‐response relations could be established without direct reinforcement. In AB training for 12 undergraduates, higher rates of touches to a white circle on the monitor screen (A1) produced two stimuli (B1 and B2) on half of the trials, whereas lower rates (A2) produced the same effect on ...
Masanobu Kuwahara +3 more
openaire +1 more source
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
EPPR Report to SAO, Nov. 2009 [PDF]
Arctic Council Emergency, Preparedness, Prevention, Response (EPPR) Working Group Report to the SAO Meeting, November 12 – 13, 2009, Copenhagen ...
Arctic Council, Emergency, Preparedness, Prevention, Response (EPPR)
core +1 more source
Ensuring the continuity of essential health services during mpox response in the African region
N ...
Miriam Nanyunja +11 more
doaj +1 more source
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
Artificial molecular machines and motors—Design and control of nanoscale motion
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley +1 more source
Introduction Public health today is challenged by a wide array of hazards that threaten humans, often resulting in high rates of morbidity and mortality when they strike. These events should be detected and responded to as early as possible to save lives
George Sie Williams +15 more
doaj +1 more source
Metastatic niche shaped by host factors influences disseminated cancer cell fate
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward +2 more
wiley +1 more source
Right-to-know compliance guidance
Electronic data.; Title from PDF cover (viewed Dec. 8, 2006).; "October 2006."; Previously published: Emergency planning and community right-to-know guidance for Connecticut local emergency planning committees.
core +1 more source

