Results 71 to 80 of about 570,548 (262)
Artificial Intelligence for Emergency Response
CoRR, 2023 This is a pre-print for a book chapter to appear in Vorobeychik, Yevgeniy., and Mukhopadhyay, Ayan., (Eds.). (2023). \textit{Artificial Intelligence and Society}.
openaire +2 more sources
Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
Case management of mpox: Where we are and where we desire to be
Journal of Public Health in AfricaNo abstract available.
Solomon F. Woldetsadik +10 more
doaj +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Research on Carbon Emission Accounting and the "Dual Carbon" Transformation Path of Industrial Parks
南方能源建设[Introduction] As an important carrier of China's industrialization and urbanization, industrial parks not only provide a large amount of infrastructure and public services, but also become the main source of carbon emission in China and an important ...
Zhong WANG +4 more
doaj +1 more source
Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines
FEBS Open Bio, EarlyView.Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart +7 more
wiley +1 more source
Zhongguo gonggong weishengObjectiveTo analyze the epidemiological characteristics and pathogens of foodborne diseases among children aged 0 – 3 years in Guangzhou city, Guangdong province, to provide data for the prevention and control of diseases in the population ...
Jiali LONG +8 more
doaj +1 more source
Emerging Themes in Epidemiology, 2016 Background Cluster surveys provide rapid but representative estimates of key nutrition indicators in humanitarian crises. For these surveys, an accurate estimate of the design effect is critical to calculate a sample size that achieves adequate precision
Erin N. Hulland +3 more
doaj +1 more source
FEBS Open Bio, EarlyView.Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero +5 more
wiley +1 more source