Results 41 to 50 of about 189,472 (358)
Borocarbonitride (BCN) materials have shown significant potential as photocatalysts for hydrogen production. However, traditional bulk BCN exhibits only moderate photocatalytic activity.
Zhishan Luo +6 more
doaj +1 more source
Congenital spinal malformation, a significant birth defect with unclear etiology, has been increasingly associated with environmental factors in recent studies.
Yuwei Gao +7 more
doaj +1 more source
In order to biomimetic synthesize hydroxyapatite similar to natural bone. Hydroxyapatite (HAP) is biomimetic synthesized in simulated body fluid (SBF) by addition of imidazole-4,5-dicarboxylic acid grafted chitosan (IDACS).
Zhangxu Chen +4 more
doaj +1 more source
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
Morphological and Developmental Features of Stone Cells in Eriobotrya Fruits
Some members of the Rosaceae family, particularly pear, contain stone cells in their fruits. Although stone cells in pear fruits are well studied, relatively little attention has been given to loquat stone cells.
Shoukai Lin +14 more
doaj +1 more source
The global production volume of plastics continues to rise. The continued growth in plastics production has not only led to an increasing volume of plastic waste released into the environment but has also contributed to food waste. Plastic polymers released into environment can be slowly degraded by microorganisms, heat, oxidation, light, or hydrolysis.
openaire +2 more sources
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto +8 more
wiley +1 more source
Effect of impurities on morphology and growth mode of (111) and (001) epitaxial-like ScN films
ScN material is an emerging semiconductor with an indirect bandgap. It has attracted attention for its thermoelectric properties, use as seed layers, and for alloys for piezoelectric application.
Eklund, Per +4 more
core +1 more source
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source

