Results 51 to 60 of about 1,703,563 (303)

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

open access: yesFEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell   +2 more
wiley   +1 more source

Interactions of Coated-Gold Engineered Nanoparticles with Aquatic Higher Plant Salvinia minima Baker

open access: yesNanomaterials, 2021
The study investigated the interactions of coated-gold engineered nanoparticles (nAu) with the aquatic higher plant Salvinia minima Baker in 2,7, and 14 d.
Ntombikayise Mahaye   +2 more
doaj   +1 more source

A Review of Traditional and Emerging Residual Chlorine Quenchers on Disinfection By-Products: Impact and Mechanisms

open access: yes, 2023
Disinfection by-products (DBPs) are the most common organic contaminants in tap water and are of wide concern because of their highly developmental toxic, cytotoxic, and carcinogenic properties.
Zhijing Zhao   +7 more
core   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

Biomimetic Synthesis of Hydroxyapatite in Presence of Imidazole-4,5-dicarboxylic Acid Grafted Chitosan for Removing Chromium(VI)

open access: yesJournal of Nanotechnology, 2018
In order to biomimetic synthesize hydroxyapatite similar to natural bone. Hydroxyapatite (HAP) is biomimetic synthesized in simulated body fluid (SBF) by addition of imidazole-4,5-dicarboxylic acid grafted chitosan (IDACS).
Zhangxu Chen   +4 more
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Effective Communication for Emerging Contaminants: Using Audience-Focused Strategies to Overcome Challenges

open access: yes, 2019
As our scientific understanding of emerging contaminants grows through improved analytical methods, increased environmental monitoring, and ongoing health risk assessment we also face a growing challenge to communicate about emerging contaminants and the
Nyquist, Katie
core   +1 more source

Sources, Fate, and Detection of Dust-Associated Perfluoroalkyl and Polyfluoroalkyl Substances (PFAS): A Review

open access: yes, 2023
The occurrence of sand and dust storms (SDSs) is essential for the geochemical cycling of nutrients; however, it is considered a meteorological hazard common to arid regions because of the adverse impacts that SDSs brings with them.
Muhammad Faizan Khan   +2 more
core   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

open access: yesMolecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang   +9 more
wiley   +1 more source

Getting Ahead of Emerging Contaminants with the Class Concept [PDF]

open access: yes, 2019
Growing concern about the presence of highly fluorinated chemicals (PFAS) in drinking water has brought increased recognition of broader emerging contaminants issues.
Bruton, Thomas
core  

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