Results 51 to 60 of about 189,472 (358)

One Health in food safety and security education: Subject matter outline for a curricular framework. [PDF]

, 2017
Educating students in the range of subjects encompassing food safety and security as approached from a One Health perspective requires consideration of a variety of different disciplines and the interrelationships among disciplines. The Western Institute
Angelos, John A, Arens, Amanda L, Cadriel, Jessica L, Johnson, Heather A, Osburn, Bennie I   +4 more
core   +3 more sources

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Assessment of POPs in foods from western China: Machine learning insights into risk and contamination drivers

Environment International
Persistent organic pollutants (POPs), including PCDD/Fs, PCBs, and PBDEs, are major environmental and food safety concerns due to their bioaccumulative and toxic properties. However, comprehensive research on the concentrations and influencing factors of
Dasheng Lu, Yuanjie Lin, Sunyang Le, Yuhang Chen, Chao Feng, Zixin Qian, Guoquan Wang, Jingguang Li, Ping Xiao   +8 more
doaj   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source

An assessment of two decades of contaminant monitoring in the Nation’s Coastal Zone. [PDF]

, 2008
Executive Summary: Information found in this report covers the years 1986 through 2005. Mussel Watch began monitoring a suite of trace metals and organic contaminants such as DDT, PCBs and PAHs.
Apeti, D. A., Christensen, J. D., Kimbrough, K. L., Lauenstein, G. G.   +3 more
core  

Impacts of Climate Change on indirect human exposure to pathogens and chemicals from agriculture [PDF]

, 2008
Objective: Climate change is likely to affect the nature of pathogens and chemicals in the environment and their fate and transport. Future risks of pathogens and chemicals could therefore be very different from those of today.
Adhikari A, Alistair B.A. Boxall, Anthony Hardy, David B. Turley, David Stone, Edward Topp, Elizabeth M.H. Wellington, European Communities, Food and Agriculture Organization, Gale P, Giovanni Leonardi, Githecko AK, Gordon Nichols, Haines A, Hawkes C, Kerry Walsh, Laura Burgin, Laura Potts, Leonard S. Levy, Patterson DT, Peter D. Falloon, Philip M. Haygarth, R. Sari Kovats, Richard J. Williams, Sabine Beulke, Simon A. Parsons, Tatiana Boucard, Thomas Hutchinson, van den Berg H   +28 more
core   +5 more sources

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Behaviour of emerging contaminants in sewage sludge after anaerobic digestion [PDF]

, 2016
Nowadays, there is an increasing concern over the presence of contaminants in the aquatic environment, where they can be introduced from wastewater after their incomplete removal in the treatment plants.
Boix Sales, Clara, Fabregat-Safont, David, Hernandez, Felix, Ibáñez, Maria, Morales, E., Pastor, L., Sancho, Juan V, Sánchez-Ramírez, J. E.   +7 more
core   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

Molecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns, Jaclyn S. Long, Sergio Lilla, Kelly Hodge, Marcus J. G. W. Ladds, Colin Nixon, Paula Fernández‐Palanca, Sara Zanivan, Pilar Acedo, Stephen P. Pereira, Kevin M. Ryan   +10 more
wiley   +1 more source

Contamination [PDF]

, 2011
Soil contamination occurs when substances are added to soil, resulting in increases in concentrations above background or reference levels. Pollution may follow from contamination when contaminants are present in amounts that are detrimental to soil ...
Bacon, J., Cundill, A., Dale, P., Fordyce, F.M., Fowler, D., Hedmark, A., Hern, A., Skiba, U.   +7 more
core   +1 more source