Results 141 to 150 of about 1,561,128 (291)

Performance and challenges of malaria rapid diagnostic tests in endemic regions of Africa

Scientific Reports
Rapid diagnostic tests (RDTs) have revolutionized malaria diagnosis, playing a crucial role in improving timely treatment and supporting surveillance efforts, especially in resource-limited settings.
Fiyinfoluwa Demilade Ojeniyi, Adeola Oluwakemi Ayoola, Olajumoke Ibitoye, Oluyinka Oladele Opaleye, Olugbenga Adekunle Olowe, Leonard Ona Ehigie, Bolaji N. Thomas, Olusola Ojurongbe   +7 more
doaj   +1 more source

Ganoderma lucidum: Unutilized natural medicine and promising future solution to emerging diseases in Africa. [PDF]

Front Pharmacol, 2022
Oke MA, Afolabi FJ, Oyeleke OO, Kilani TA, Adeosun AR, Olanbiwoninu AA, Adebayo EA.   +6 more
europepmc   +1 more source

International Network for Capacity Building for the Control of Emerging Viral Vector-Borne Zoonotic Diseases: Arbo-Zoonet [PDF]

, 2009
Arboviruses are arthropod-borne viruses, which include West Nile fever virus (WNFV), a mosquito-borne virus, Rift Valley fever virus (RVFV), a mosquito-borne virus, and Crimean-Congo haemorrhagic fever virus (CCHFV), a tick-borne virus.
Ahmed, J., Bouloy, M., Calistri, P., Chevalier, V., Drosten, C., Ergonul, O., Estrada-Pena, A., Fooks, A.R., Mirazimi, A., Moormann, R.J.M., Paweska, J., Seitzer, U., Tordo, N., Unger, H., Vatansever, Z., Yin, H.   +15 more
core  

Plasma extrachromosomal circular DNA as a biomarker in EGFR‐targeted therapy of non‐small cell lung cancer

Molecular Oncology, EarlyView.
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard, Sarmad Mehmood, Eva Boysen Fynboe Ebert, Peter Meldgaard, Anindya Dutta, Boe S. Sorensen   +5 more
wiley   +1 more source

Structural and Phylogenetic Analysis of CXCR4 Protein Reveals New Insights into Its Role in Emerging and Re-Emerging Diseases in Mammals. [PDF]

Vaccines (Basel), 2023
Naheed F, Mumtaz R, Shabbir S, Jamil A, Asif AR, Rahman A, Ahmad HI, Essa M, Akhtar H, Mahmoud SF, Alghamdi FO, Amari HAA, Chen J.   +12 more
europepmc   +1 more source

Night at the museum: Contribution of small RNA from historical herbarium specimens in the reconstruction of evolutionary histories of geminiviruses [PDF]

, 2019
Emerging infectious diseases of plants, almost half of which are caused by viruses, are recognized as a growing threat to global food security. However, little is known about the evolutionary processes and ecological factors that underlie the emergence ...
Becker, Nathalie, Campos, Paola, Duvermy, Arnaud, Filloux, Denis, Lett, Jean-Michel, Martin, Darren Patrick, Rieux, Adrien, Roumagnac, Philippe, Scussel, Sarah   +8 more
core  

Glycosylated LGALS3BP is highly secreted by bladder cancer cells and represents a novel urinary disease biomarker

Molecular Oncology, EarlyView.
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece, Giulio Lovato, Ilaria Cela, Arianna Mercatelli, Benedetta Ferro, Jussi Nikkola, Sara Pagotto, Tommaso Grottola, Vincenzo De Laurenzi, Rossella Cicchetti, Antonio Marchetti, Luigi Schips, Rossano Lattanzio, Stefano Iacobelli, Emily Capone, Peter Black, Mads Daugaard, Michele Marchioni, Gianluca Sala   +18 more
wiley   +1 more source

Is Better Standardization of Therapeutic Antibody Quality in Emerging Diseases Epidemics Possible? [PDF]

Front Immunol, 2022
Ravlić S, Hećimović A, Kurtović T, Ivančić Jelečki J, Forčić D, Slović A, Kurolt IC, Mačak Šafranko Ž, Mušlin T, Rnjak D, Jakšić O, Sorić E, Džepina G, Đaković Rode O, Kujavec Šljivac K, Vuk T, Jukić I, Markotić A, Halassy B.   +18 more
europepmc   +1 more source

Transposable Elements, Inflammation, and Neurological Disease. [PDF]

, 2019
Transposable Elements (TE) are mobile DNA elements that can replicate and insert themselves into different locations within the host genome. Their propensity to self-propagate has a myriad of consequences and yet their biological significance is not well-
Macia, Angela, Muotri, Alysson R, Saleh, Aurian   +2 more
core  

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

Molecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia, Noelia Moares, Wenjie Yi‐He, Rosa Luna‐Espejo, Ricardo Fernandez‐Cisnal, Javier Ocaña‐Cuesta, Juan P. Muñoz‐Miranda, Antonio Gabucio, Cecilia M. Fernandez‐Ponce, Francisco Garcia‐Cozar   +9 more
wiley   +1 more source