Results 121 to 130 of about 594,306 (305)

Age‐Related Characteristics of SYT1‐Associated Neurodevelopmental Disorder

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives We describe the clinical manifestations and developmental abilities of individuals with SYT1‐associated neurodevelopmental disorder (Baker‐Gordon syndrome) from infancy to adulthood. We further describe the neuroradiological and electrophysiological characteristics of the condition at different ages, and explore the associations ...
Sam G. Norwitz, Josefine Eck, Joel S. Winston, Kate Baker   +3 more
wiley   +1 more source

Infectious Diseases Institute [PDF]

, 2017
IMPACT. 1: Provide infectious diseases communications and resources for the community, key stakeholders, and policy makers.OSU PARTNERS: College of Arts and Sciences; College of Dentistry; College of Education and Human Ecology; College of Engineering ...
Oglesbee, Mike
core  

In‐Depth Profiling Highlights the Effect of Efgartigimod on Peripheral Innate and Adaptive Immune Cells in Myasthenia Gravis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Myasthenia gravis (MG) is an autoimmune disorder characterized by antibody‐mediated complement activation. Efgartigimod, a neonatal Fc receptor (FcRn) antagonist, is approved for treating generalized MG (gMG). However, its modulatory effects on upstream innate and adaptive immune cells remain largely unexplored.
Lei Jin, Liu Dong, Ying Wang, Dingxian He, Chong Yan, Jianying Xi, Haoqin Jiang, Yu Shi, Ming Guan, Chongbo Zhao, Jie Song, Sushan Luo   +11 more
wiley   +1 more source

Anthelmintic Activity of Ethanolic and Aqueous Extracts of Khaya grandifoliola Stem Bark against Heligmosomoides polygyrus: In Vitro and In Silico Approaches

Journal of Tropical Medicine
Background. Parasitic infection remains a serious health trade for humans and livestock. The purpose of this study was to present scientific proof of the anthelmintic properties of Khaya grandifoliola, which the native population uses to cure ...
Noumedem Anangmo Christelle Nadia, Mahdi Yaghoobi, Yamssi Cédric, Masoud Besati, Yungong Misparine Kiki, Ngouyamsa Nsapkain Aboubakar Sidiki, Mounvera Abdel Azizi, Vincent Khan Payne, Haibo Hu   +8 more
doaj   +1 more source

Super‐Refractory Status Epilepticus (SRSE) in a Patient With Compound Heterozygous OPA1 Variants: Case Report and Literature Review

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi, Lara Basovic, Christopher Michael McGraw   +2 more
wiley   +1 more source

CX3CL1 in Early Detection of Alzheimer's Disease: Plasma Dynamics Across Age and Disease Stages

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Backgrounds Alzheimer's disease (AD) is characterized by amyloid‐beta plaques, tau tangles, and neuroinflammation. C‐X3‐C motif chemokine ligand 1 (CX3CL1, also known as fractalkine), a neuroimmune chemokine implicated in AD pathogenesis, shows inconsistent alterations in plasma/serum across studies.
Ling Wang, Yujie Liu, Fei Li, Xuelin Li, Lanlan Li, Jie Zhang, Yali Xu   +6 more
wiley   +1 more source

Adaptive mutations in HA of avian H9N2 influenza viruses facilitate their transmission to swine

Veterinary Research
The cross-species transmission of avian H9N2 influenza viruses to swine increases the risk of viral adaptation to mammalian hosts. However, the mechanisms by which these H9 viruses can overcome the barriers posed by swine hosts have not yet been fully ...
Jia Wang, Peiwen Chen, Qiwei Liu, Sixia Huang, Maocai Wu, Dan’er Wei, Wenshan Hong, Tommy Tsan-Yuk Lam, Huachen Zhu, Yi Guan   +9 more
doaj   +1 more source

Emerging infectious diseases [PDF]

Public Health Research and Practice, 2016
openaire   +2 more sources

Aspek-aspek Ekologi dan Sosial dalam Penanggulangan "Emerging Infectious Diseases" [PDF]

, 1997
Ecological and social fators play very important roles in the control of emerging infectious diseases, beside case management, surveillance and laboratory examinations.
S, S. S. (Sri), Sudomo, M. (M), Waluyo, I. (Imam)   +2 more
core  

Effectiveness and Safety of Baricitinib for Juvenile Idiopathic Arthritis–Associated Uveitis or Chronic Anterior Antinuclear Antibody–Positive Uveitis

Arthritis Care &Research, EarlyView.
Objective To evaluate the efficacy and safety of baricitinib in pediatric patients with active juvenile idiopathic arthritis–associated uveitis (JIA‐U) or chronic anterior antinuclear antibody–positive uveitis, who had an inadequate response to methotrexate (MTX) or biologic disease‐modifying antirheumatic drugs (bDMARDs).
Athimalaipet V. Ramanan, Catherine M. Guly, Gabriele Simonini, Stuart Y. Keller, Priyanka Sen, Thorsten Holzkaemper, Joana Araújo, Pierre Quartier   +7 more
wiley   +1 more source