Results 61 to 70 of about 4,947,670 (279)

Developmental, Neuroanatomical and Cellular Expression of Genes Causing Dystonia

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Dystonia is one of the most common movement disorders, with variants in multiple genes identified as causative. However, an understanding of which developmental stages, brain regions, and cell types are most relevant is crucial for developing relevant disease models and therapeutics.
Darren Cameron, Nicholas E. Clifton, Daniel Cabezas de la Fuente, Peter Holmans, Nicholas J. Bray, Kathryn J. Peall   +5 more
wiley   +1 more source

Variably Protease‐Sensitive Prionopathy: Two New Cases With Motor Neuron‐Dementia Syndrome

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT We describe two patients with variably protease‐sensitive prionopathy (VPSPr) who developed progressive upper motor neuron symptoms, insomnia, behavioral and cognitive decline, compatible with primary lateral sclerosis associated with frontotemporal dementia (FTD).
María Elena Erro, María Victoria Zelaya, Hasier Eraña, Javier Sánchez Ruiz de Gordoa, Fermín García‐Amigot, Anika Simonovska‐Serra, María Cristina Caballero, Isidre Ferrer, Ellen Gelpi, Ivonne Jericó, Joaquín Castilla   +10 more
wiley   +1 more source

A Survey on Computing-in-Memory (CiM) and Emerging Nonvolatile Memory (NVM) Simulators

Chips
Modern computer applications have become highly data-intensive, giving rise to an increase in data traffic between the processor and memory units. Computing-in-Memory (CiM) has shown great promise as a solution to this aptly named von Neumann bottleneck ...
John Taylor Maurer, Ahmed Mamdouh Mohamed Ahmed, Parsa Khorrami, Sabrina Hassan Moon, Dayane Alfenas Reis   +4 more
doaj   +1 more source

Emergence of Robust Memory Manifolds

PRX Life
The ability to store continuous variables in the state of a biological system (e.g., a neural network) is critical for many behaviors. Most models for implementing such a memory manifold require hand-crafted symmetries in the interactions or precise fine-tuning of parameters.
Tankut Can, Kamesh Krishnamurthy
openaire   +2 more sources

Neuropsychiatric Symptoms Mimicking Dementia in a Patient Treated With Imatinib

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Tyrosine kinase inhibitors are the cornerstone of chronic myeloid leukemia treatment. Newer agents have more potency and a broader spectrum of action, but also a higher potential for neuropsychiatric side effects. We present a case of a patient on imatinib who developed progressive cognitive, mood, and behavioral alterations.
Ashley Jones, Samuele Bonomi, Keith E. Stockerl‐Goldstein, Randall J. Bateman   +3 more
wiley   +1 more source

Emerging 2D Ferroelectric Devices for In‐Sensor and In‐Memory Computing

Advances in Materials
The quantity of sensor nodes within current computing systems is rapidly increasing in tandem with the sensing data. The presence of a bottleneck in data transmission between the sensors, computing, and memory units obstructs the system's efficiency and ...
Chunsheng Chen, Yaoqiang Zhou, Lei Tong, Yue Pang, Jianbin Xu   +4 more
semanticscholar   +1 more source

Unraveling the Molecular Mechanisms of Glioma Recurrence: A Study Integrating Single‐Cell and Spatial Transcriptomics

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Glioma recurrence severely impacts patient prognosis, with current treatments showing limited efficacy. Traditional methods struggle to analyze recurrence mechanisms due to challenges in assessing tumor heterogeneity, spatial dynamics, and gene networks.
Lei Qiu, Yinjiao Fei, Jiaxuan Ding, Kexin Shi, Jinyan Luo, Yuchen Zhu, Xingjian Sun, Gefei Jiang, Yuandong Cao, Weilin Xu, Shu Zhou   +10 more
wiley   +1 more source

Emerging horizons in phase-change materials for non-volatile memory

Materials Today Advances
Phase Change Memory (PCM) technology, particularly utilizing GeTe-based materials, has emerged as a compelling alternative to traditional nonvolatile memory systems, offering significant advancements in speed, scalability, and endurance.
Yan Chen, Yuqiao Le, Lei Chen, Haisong Liu, Tangyou Sun, Xingpeng Liu, Fabi Zhang, Haiou Li, XinXin Hu, Ying Peng, Chengyan Liu, Min Hong   +11 more
doaj   +1 more source

Clinical Spectrum and Outcomes of SOX1 Antibody‐Associated Paraneoplastic Neurological Syndromes: A Chinese Cohort Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background SOX1 antibody‐positive paraneoplastic neurological syndromes (PNS) exhibit significant population‐specific clinical heterogeneity. While Western cohorts predominantly manifest Lambert‐Eaton myasthenic syndrome (65%–80%), comprehensive clinical characterization and treatment response data in Asian populations remain critically ...
Jin‐Long Ye, Zu‐Ying Kuang, Bo Li, Meng‐Qiu Pan, Li‐Hua Zhou, Yang‐Yang Dai, Si‐Fen Xie, Xian‐Guang Lin, Ye‐Peng Hu, Li‐Hong Jiang, Zhan‐Hang Wang, Wei‐Jing Zhang   +11 more
wiley   +1 more source

Sleep deprivation-induced memory impairment: exploring potential interventions

Frontiers in Psychiatry
Sleep’s crucial role in memory consolidation is well-established, with neuroimaging and sleep stage analysis revealing the intricate processes involved.
Yisheng Fan, Jianfeng Li, Shanfeng Qiao
doaj   +1 more source