Results 51 to 60 of about 417 (119)

When Emerging Fungal Infections Mimic Tuberculosis: First Reported Case of Invasive <i>Emergomyces europaeus</i> Infection in a Man With Immunocompromise Living in France. [PDF]

Open Forum Infect Dis
Abstract Emergomycosis is an emerging thermally dimorphic fungal infection primarily observed in individuals with HIV and is associated with cutaneous, pulmonary, or disseminated manifestations. We report the first case of invasive infection by Emergomyces europaeus involving both the lungs and bone marrow in a person with ...
Cottrel C, Ramsamy N, Fruquière E, Melone A, Lanternier F, Garcia-Hermoso D, Debourgogne A.   +6 more
europepmc   +4 more sources

Systemic Mycoses by Novel Onygenalean Fungal Pathogens Emergomyces spp and Blastomyces percursus in Rwanda. [PDF]

Open Forum Infect Dis
Abstract We report 2 cases of infection by fungi unprecedented in Rwanda. One patient with emergomycosis presented with disseminated disease and prominent cutaneous involvement and one patient with African blastomycosis had cutaneous and osseous disease. These cases illustrate the clinicopathologic and molecular traits of novel dimorphic
Laga AC, Ruhangaza D, Izimukwiye AI, Vilela R, Mendoza L.   +4 more
europepmc   +3 more sources

Model figure showing the conservation of Cbp1 sequence, structure, and lytic function in Ajellomycetacea species that are human fungal pathogens.

, 2022
Based on predicted protein homology and syntenic regions of the gene, homologs of Cbp1 were identified in the genomes Histoplasma, Emergomyces, Emmonsia, and Paracoccidioides species but not Blastomyces, correlating with its largely extracellular ...
Lucian Duvenage (12908693), Jennifer C. Hoving (12908699), Oren Rosenberg (4849222), Bevin C. English (4474726), Mark Voorhies (435858), Rosa A. Rodriguez (12908696), Anita Sil (89454), Dinara Azimova (12908690), Nadia Herrera (1931170)   +8 more
core   +1 more source

A novel dimorphic pathogen, Emergomyces orientalis (Onygenales), agent of disseminated infection [PDF]

Mycoses, 2017
SummaryA novel dimorphic fungus, Emergomyces orientalis sp. nov. a close relative of systemic pathogens in the family Ajellomycetaceae (Blastomyces, Histoplasma). The fungus is reported in a 64‐year‐old male from Shanxi, China. The patient developed disseminated skin lesions, productive cough with fever and showed nodular opacities in his left lung on ...
Peng, Wang, Chris, Kenyon, Sybren, de Hoog, Lina, Guo, Hongwei, Fan, Hongrui, Liu, Zhongwei, Li, Ruiyuan, Sheng, Ying, Yang, Yanping, Jiang, Li, Zhang, Yingchun, Xu   +11 more
openaire   +3 more sources

Emergomykose: eine weltweit auftretende systemische Mykose durch thermal dimorphe Pilze [PDF]

, 2018
Unter Emergomykosen werden systemische, potenziell letal verlaufende Infektionen mit Lungenund/ oder Hautbeteiligung durch ein neu beschriebenes Genus thermal dimorpher Pilze verstanden.
Wilmes, Dunja, Rickerts, Volker
core   +1 more source

Emergomyces species contain Cbp1 homologs in their genomes that can be expressed and secreted by the Hc G217B strain but are insufficient to confer macrophage lysis.

, 2022
A. InstantBlue stained SDS-PAGE gel of culture supernatants of Hc G186AR, Hc H88, Hc G217B, Hc G217B cbp1 mutant, and Hc G217B cbp1 mutant expressing the G217B, P. americana (Pb03), E. crescens, Es. orientalis, Es. pasteurianus_1, Es.
Lucian Duvenage (12908693), Jennifer C. Hoving (12908699), Oren Rosenberg (4849222), Bevin C. English (4474726), Mark Voorhies (435858), Rosa A. Rodriguez (12908696), Anita Sil (89454), Dinara Azimova (12908690), Nadia Herrera (1931170)   +8 more
core   +1 more source

Potential model for exposure and pathogenesis of Emergomyces.

, 2019
1) Emergomyces species exist in soil in a mold phase, from where 2) conidia are released and aerosolized. 3) Upon inhalation by humans, the conidia undergo a temperature-dependent transformation in the lungs to yeast-like cells that replicate by budding ...
Karolina Dukik (828546), Robert Colebunders (10697), Tsidiso G. Maphanga (7407023), Christina A. Cuomo (7407035), Nelesh P. Govender (7407020), Lynne Sigler (828547), J. Claire Hoving (7407029), Sybren de Hoog (11778), Chris Kenyon (413928), Alfred Botha (828549), Ilan S. Schwartz (7407017), Jose F. Muñoz (7407032), Yanping Jiang (828548), Barbra Toplis (7407026)   +13 more
core   +1 more source

Emerg Infect Dis

Emergomyces is a newly described dimorphic fungus genus; it may cause fatal infections in immunocompromised patients, but diagnosis is often delayed. We report a case of disseminated emergomycosis caused by the novel species Emergomyces orientalis in a ...

core   +4 more sources

BMDM infections with Hc strains expressing tagged versions of Hc or Pb03 Cbp1.

, 2022
A. BMDMs were mock-infected (uninf) or infected with the “WT” strain of Hc G217B ura5- carrying the vector control or the Hc G217B cbp1 mutant strain carrying either the URA5 vector control or 3 independent transformants of Pb03 Cbp1 tagged with 3XFLAG ...
Lucian Duvenage (12908693), Jennifer C. Hoving (12908699), Oren Rosenberg (4849222), Bevin C. English (4474726), Mark Voorhies (435858), Rosa A. Rodriguez (12908696), Anita Sil (89454), Dinara Azimova (12908690), Nadia Herrera (1931170)   +8 more
core   +1 more source

Global geographic distribution of reported cases of emergomycosis [1, 4–7, 10–19, 28–30].

, 2019
Each icon represents a single case except for Emergomyces africanus in South Africa, as indicated. Map created by Institute of Tropical Medicine, Antwerp.
Karolina Dukik (828546), Robert Colebunders (10697), Tsidiso G. Maphanga (7407023), Christina A. Cuomo (7407035), Nelesh P. Govender (7407020), Lynne Sigler (828547), J. Claire Hoving (7407029), Sybren de Hoog (11778), Chris Kenyon (413928), Alfred Botha (828549), Ilan S. Schwartz (7407017), Jose F. Muñoz (7407032), Yanping Jiang (828548), Barbra Toplis (7407026)   +13 more
core   +1 more source