Results 111 to 120 of about 13,194 (271)
Annals of Clinical Microbiology and Antimicrobials, 2004 Background Amoebiasis is a major public health problem in tropical and subtropical countries. Although a number of antiamoebic agents are used for its treatment, yet the susceptibility data on clinical isolates of Entamoeba histolytica and Entamoeba ...
Mahajan Ramesh +4 more
doaj +1 more source
Chemistry &Biodiversity, Volume 22, Issue 1, January 2025.Abstract Leishmaniasis is a vector‐borne, parasitic disease affecting millions of people and animals worldwide. Current therapeutic options have proven to be ineffective in both treating the disease and preventing its spread. As a result, new drugs must be developed to effectively combat this disease.
Nadine Henning +5 more
wiley +1 more source
Emetine in Amoebic Dysentery [PDF]
Annals of Tropical Medicine & Parasitology, 1914 n ...
openaire +2 more sources
5-HT2a receptor in mPFC influences context-guided reconsolidation of object memory in perirhinal cortex [PDF]
, 2018 Context-dependent memories may guide adaptive behavior relaying in previous experience while updating stored information through reconsolidation. Retrieval can be triggered by partial and shared cues.
Bekinschtein, Pedro Alejandro +5 more
core +1 more source
Human Mutation, Volume 2025, Issue 1, 2025.COL4A5 gene variants could result in the X‐linked Alport syndrome 1, dominant inheritance (XLAS1) (Online Mendelian Inheritance in Man (OMIM) #301050). The splicing changes can be identified through targeted RNA sequencing (RNA seq), but obtaining accessible patient samples from urine cells and skin fibroblasts is challenging.
Yixiao Li +13 more
wiley +1 more source
Enhancement of the IFN-β-induced host signature informs repurposed drugs for COVID-19
Heliyon, 2020 Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a causative agent for the outbreak of coronavirus disease 2019 (COVID-19). This global pandemic is now calling for efforts to develop more effective COVID-19 therapies.
Chen-Tsung Huang +8 more
doaj +1 more source
Emetine Toxicity with Electrocardiographic Abnormalities [PDF]
Circulation, 1956 Seven case histories are presented illustrating various aspects of the noxious effects of emetine on the heart. T-wave changes, S-T segment deviations, and partial heart block are demonstrated. A case of frank myocardial infarction in a young man occurring during the administration of emetine is described.
openaire +3 more sources
Evidence for a regulatory role of Cullin-RING E3 ubiquitin ligase 7 in insulin signalling [PDF]
, 2014 Dysfunctional regulation of signalling pathways downstream of the insulin receptor plays a pivotal role in the pathogenesis of insulin resistance and type 2 diabetes.
Charron, Maureen J. +11 more
core +1 more source
How CBX proteins regulate normal and leukemic blood cells
FEBS Letters, Volume 598, Issue 22, Page 2788-2806, November 2024.CBX proteins are epigenetic reader proteins that can recognize histone modifications and thereby dictate cell fate. In this review, we describe how CBX proteins dictate cell fate in normal hematopoiesis and leukemia. In addition, we discuss which CBX proteins can promote leukemic cell growth and whether pharmacological inhibition of CBX proteins can ...
Anne P. de Groot, Gerald de Haan
wiley +1 more source
Analysis of Mitochondrial Protein Synthesis: De Novo Translation, Steady-State Levels, and Assembled OXPHOS Complexes. [PDF]
, 2018 Mitochondria are multifunctional organelles with their own genome and protein synthesis machinery. The 13 proteins encoded by mitochondrial DNA (mtDNA) are core subunits of the oxidative phosphorylation (OXPHOS) system producing the majority of cellular ...
D'Amico +9 more
core +1 more source