Results 91 to 100 of about 6,696 (158)

Investigating antimalarial drug interactions of emetine dihydrochloride hydrate using CalcuSyn-based interactivity calculations - Fig 6

, 2017
The constant ratio combinations of dihydroartemisinin-emetine (a,b), chloroquine-emetine (c,d) and atovaquone-emetine (e,f) using CalcuSyn. Parasite viability was analysed after 72 hours using the SG-FCM method.
Jon Deakin (3813211), May Rajab (3813214), Holly Matthews (242183), Maryam Idris-Usman (3813217), Niroshini J. Nirmalan (1275435)   +4 more
core   +1 more source

Emetine is an early inhibitor of HCMV replication.

, 2016
A) Emetine does not inhibit HCMV entry. Cells were treated with emetine (75 nM), GCV (10 μM), and CpG 2006 (10 μM) 24 h prior to infection. Cells were infected with HCMV and treated with compounds for 90 min.
Xin Hu (38924), Xin Xu (11989), Rupkatha Mukhopadhyay (106864), Andrés E. Dulcey (2475010), Juan J. Marugan (191299), Ravit Arav-Boger (116842), Amy Q. Wang (1395658), Yu-Pin Su (2851958), Noel Southall (187625), Marc Ferrer (191300), Lesley Mathews Griner (2851961), Elena Barnaeva (1316694), Wenjuan Ye (2088499), Sujayita Roy (409389), Rajkumar Venkatadri (1314918)   +14 more
core   +1 more source

In-silico evaluation of natural alkaloids against the main protease and spike glycoprotein as potential therapeutic agents for SARS-CoV-2.

PLoS ONE
Severe Acute Respiratory Syndrome Corona Virus (SARS-CoV-2) is the causative agent of COVID-19 pandemic, which has resulted in global fatalities since late December 2019.
Mohibullah Shah, Ramsha Yamin, Iqra Ahmad, Gang Wu, Zainab Jahangir, Amen Shamim, Haq Nawaz, Umar Nishan, Riaz Ullah, Essam A Ali, Sheheryar, Ke Chen   +11 more
doaj   +1 more source

The expectorant action of cephaeline, emetine and 2-dehydroemetine

, 1964
Cephaeline, emetine and 2-dehydroemetine were administered, as the dihydrochlorides, in doses from 0.1 to 81 mg/kg body weight, orally and subcutaneously to 135 rabbits and 92 cats arranged for the collection of respiratory tract fluid.
Lois M Knight, Eldon M Boyd
core   +1 more source

The effects of emetine on the myocardium

, 1963
A number of drugs have achieved notoriety for their toxicity to the myocardium. Of those used in tropical medicine antimony and emetine are outstanding examples.
Peter P. Turner
core  

Cross-Family Mechanistic Analysis of Plant Alkaloids Against Neglected Arboviruses and Related RNA Viruses. [PDF]

Molecules
Régis M, Sanchez Moreno MF, Germain H, Mérindol N, Desgagné-Penix I.   +4 more
europepmc   +1 more source

<i>FOXP3</i> deep intronic variant underlying IPEX. [PDF]

J Hum Immun
Gaufryau P, Stolzenberg MC, Lambert N, Peters P, El Missaoui I, Alioua N, Hanein S, Hamici M, Nitschké P, Zhang P, Bustamante J, Neven B, Picard C, Rieux-Laucat F, Rosain J.   +14 more
europepmc   +1 more source

Emetine dihydrochloride inhibits Chikungunya virus nsP2 helicase and shows robust antiviral activity in cells and mice. [PDF]

J Biomed Sci
Sharma A, Subramani C, Shouri KA, Sharma G, Basu B, Pandey AD, Rout A, Sharma D, Jain D, Vrati S.   +9 more
europepmc   +1 more source

ELECTRICAL PROPERTIES OF RAT EXTENSOR DIGITORUM LONGUS MUSCLE AFTER CHRONIC APPLICATION OF EMETINE TO THE MOTOR NERVE.

, 1982
Muscle weakness is a side effect of the chronic administration of emetine [(-)emetine] in the treatment of amoebiasis. The precise nature of the weakness is still controversial.
MITOLO CHIEPPA D., BRYANT SH, CONTE, Diana   +2 more
core  

NFκB/IL-6/JAK2/STAT axis in myelofibrosis is a key vulnerability that is targetable and relevant to JAK2 inhibitor treatment resistance. [PDF]

Blood Cancer J
Bian H, Gangat N, Shen N, Pang J, Wald D, Tse W, Tefferi A, Yan F, Liu S.   +8 more
europepmc   +1 more source