Results 91 to 100 of about 3,767,493 (339)

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

Molecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad, Mahmood Hachim, Tom Bertin, Karolina Penderecka, Rifat Hamoudi, Saif Khan, Rui Henrique, Natalie Bergmoser, Manit Arya, Kalle Sipila, Matteo Vietri Rudan, Asif Muneer, Aamir Ahmed   +12 more
wiley   +1 more source

Results from a Second RXTE Observation of the Coma Cluster

, 2002
The RXTE satellite observed the Coma cluster for 177 ksec during November and December 2000, a second observation motivated by the intriguing results from the first 87 ksec observation in 1996.
Duane Gruber, Ensslin T. A., Kaastra J. S., Yoel Rephaeli   +3 more
core   +2 more sources

Directional `superradiant' collisions: bosonic amplification of atom pairs emitted from an elongated Bose-Einstein condensate [PDF]

, 2002
We study spontaneous directionality in the bosonic amplification of atom pairs emitted from an elongated Bose-Einstein condensate (BEC), an effect analogous to `superradiant' emission of atom-photon pairs.
A. Vardi, J. Javanainen, K. Helmerson, M. G. Moore, X. X. Yi   +4 more
core   +1 more source

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

Molecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller, Susanne Ebner, Carmen Haselrieder, Julia K. Günther, Astrid Drasche, Sophie Strich, Chiara Volani, Andrea Medici, Aleksandar Nikolajevic, Alex Deltedesco, Johannes E. Sigmund, Michael J. Blumer, Martin Hermann, Johanna Vanacker, Gerald Brandacher, Eduard Stefan, Omar Torres‐Quesada, Jakob Troppmair   +17 more
wiley   +1 more source

Fibroblast activation protein expression in the tumor microenvironment is crucial in survival prediction and differentiation of recurrent gliomas: a head-to-head comparison of 68Ga-FAPI-04 and 18F-FET in PET/CT imaging

EJNMMI Radiopharmacy and Chemistry
Background The precise differentiation of recurrent glioma from treatment-related changes, such as pseudoprogression or radiation necrosis, is essential for treatment planning and remains a significant challenge.
Tao Hua, Qi Huang, Zhirui Zhou, Weiyan Zhou, Jianbo Wen, Fang Xie, Ming Li, Yihui Guan, Dongxiao Zhuang   +8 more
doaj   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Comparison of Sub-Ppm Instrument Response Suggests Higher Detection Limits Could Be Used to Quantify Methane Emissions from Oil and Gas Infrastructure

Sensors
Quantifying and controlling fugitive methane emissions from oil and gas facilities remains essential for addressing climate goals, but the costs associated with monitoring millions of production sites remain prohibitively expensive.
Stuart N. Riddick, Mercy Mbua, Ryan Brouwer, Ethan W. Emerson, Abhinav Anand, Elijah Kiplimo, Seunfunmi Ojomu, Jui-Hsiang Lo, Daniel J. Zimmerle   +8 more
doaj   +1 more source

Radio Emission from Cosmic Ray Air Showers: Coherent Geosynchrotron Radiation [PDF]

, 2003
Cosmic ray air showers have been known for over 30 years to emit pulsed radio emission in the frequency range from a few to a few hundred MHz, an effect that offers great opportunities for the study of extensive air showers with upcoming fully digital ...
Abu-Zayyad, Agnetta, Allan, Allan, Allan, Aloisio, Alvarez-Muñiz, Antoni, Askaryan, Askaryan, Atrashkevich, Buniy, Castagnoli, Colgate, Dova, Falcke, Green, Greisen, Greisen, H. Falcke, Jelley, Kamata, Knapp, Lerche, Linsley, Pryke, Spencer, T. Huege, Zas   +28 more
core   +2 more sources

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source

Addressing Low-Cost Methane Sensor Calibration Shortcomings with Machine Learning

Atmosphere
Quantifying methane emissions is essential for meeting near-term climate goals and is typically carried out using methane concentrations measured downwind of the source.
Elijah Kiplimo, Stuart N. Riddick, Mercy Mbua, Aashish Upreti, Abhinav Anand, Daniel J. Zimmerle   +5 more
doaj   +1 more source