Results 31 to 40 of about 2,685,096 (249)
Land, 2022 Under the “double carbon” target, it is important to reduce carbon emissions in each region. Using exploratory spatial data analysis (ESDA), the center of gravity method, and spatial econometric models, we analyzed the characteristics and spatial ...
Zhenjun Gao +3 more
doaj +1 more source
FEBS Letters, EarlyView.We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
MitigatePlus: Research for low-emission food systems
, 2023 MitigatePlus: Research for Low-Emission Food Systems is one of the Research Initiatives in CGIAR’s new research portfolio that will deliver science and innovation to transform food, land, and water systems in a climate crisis.
Verchot, Louis; Zhang, Wei +1 more
core
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
FEBS Letters, EarlyView.How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
Frontiers in Sustainable Food SystemsLow- and middle-income countries (LMICs) are rapidly urbanizing, leading to a high demand for high-quality animal products. Production increase is seen as a key to meeting this demand and reducing the global environmental impact of low-yielding dairy ...
Marion Reichenbach +6 more
doaj +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Environmental Research LettersAlthough national emission control policies have contributed to long-term reductions in PM _2.5 levels, responses across neighboring cities remain heterogeneous, complicating the evaluation of policy effectiveness.
Jihoon Seo +6 more
doaj +1 more source
Frontiers in Environmental Science, 2021 China is the largest producer of carbon in the world. China’s construction industry has received widespread attention in recent years due to its environmental issues. However, little research has been conducted to investigate the environmental efficiency
Xiaoping Li +3 more
doaj +1 more source