Results 51 to 60 of about 199,190 (345)
Survivin and Aurora Kinase A control cell fate decisions during mitosis
Molecular Oncology, EarlyView.Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir +2 more
wiley +1 more source
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
New Symbiotic Stars from LAMOST DR10 Spectra and Multiband Photometry
The Astrophysical JournalThe Symbiotic star (SySt) is a long-period interacting binary system, typically consisting of a white dwarf (WD) and a red giant surrounded by a nebula. These systems are natural astrophysical laboratories for investigating binary star evolution. In this
Jing Chen +7 more
doaj +1 more source
Correction of UBV Photometry for Emission Lines
Open Astronomy, 2003 We investigate the effect on U,B,V magnitudes of the removal of emission lines from the spectra of some symbiotic stars and novae during their nebular phases.
Skopal A.
doaj +1 more source
Measurement of Interstellar Extinction in Emission Line Stars [PDF]
Symposium - International Astronomical Union, 1970 Usually selective interstellar extinction is derived by comparing the spectrum of a reddened star with an unreddened nearby star, preferably of the same spectral type. But in many cases this comparison is not possible, so that new methods have to be used.A direct measure of this quantity is possible when a spectrum shows a number of emission lines as ...
openaire +1 more source
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
Spectroscopy of unusual emission-line stars
The Astronomical Journal, 1988 New spectroscopic observations are reported for ten stars that have been identified in the literature as having H-alpha emission with suspected F, G, or K spectral types. Three of the stars are shown to be BE stars, two are confirmed as early-type supergiants, three show composite (F or K + B) spectra, one is a 'post-T Tauri' star, and one is an ...
openaire +1 more source
Chromospherically Active Stars in the RAVE Survey. I. The Catalogue [PDF]
, 2013 RAVE, the unbiased magnitude limited survey of the southern sky stars, contained 456,676 medium-resolution spectra at the time of our analysis. Spectra cover the CaII IRT range which is a known indicator of chromospheric activity.
Bienaymé, O. +17 more
core +2 more sources
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
A Catalog of Early-type Hα Emission-line Stars and 62 Newly Confirmed Herbig Ae/Be Stars from LAMOST Data Release 7 [PDF]
, 2022 Yun-Jin Zhang +8 more
openalex +1 more source