Results 31 to 40 of about 10,060 (266)

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

Properties of Galactic B[e] Supergiants. X. Refined Orbit and Fundamental Parameters of the HD 327083 Binary System

The Astrophysical Journal
HD 327083 is a binary system that consists of two supergiant components and exhibits the B[e] phenomenon. In this paper, we report the determination of a new set of the system’s fundamental parameters using a combination of photometric and spectroscopic ...
A. S. Nodyarov, A. S. Miroshnichenko, S. A. Khokhlov, S. V. Zharikov, A. T. Agishev, I. A. Gabitova, N. L. Vaidman, N. Manset   +7 more
doaj   +1 more source

CO rotational line emission in very red carbon stars in the Magellanic Clouds

Astronomy & Astrophysics
Stars of low and intermediate initial mass lose most of their stellar mass at the end of their lives during the asymptotic giant branch (AGB) phase. Determining their gas and dust mass-loss rates (MLRs) is crucial for quantifying the contribution of ...
Groenewegen M. A. T., Nanni A., Boyer M. L., Decin L., Goldman S. R., Justtanont K., Kerschbaum F., McDonald I., Olofsson H., Sahai R., Sloan G. C., van Loon J. Th., Vlemmings W. H. T., Zijlstra A. A.   +13 more
doaj   +1 more source

Reddening-Free Q Parameters to Classify B-Type Stars with Emission Lines

Galaxies, 2023
The emission-line B-type stars constitute a heterogeneous group. Many of these stars show similar optical spectroscopic features and color indices, making it difficult to classify them adequately by means of photometric and spectroscopic techniques. Thus,
Yael Aidelman, Lydia Sonia Cidale
doaj   +1 more source

Spectroscopic survey of emission-line stars – I. B[e] stars [PDF]

Monthly Notices of the Royal Astronomical Society, 2015
15 pages, 7 figures, accepted for publication in ...
Aret, Anna, Kraus, Michaela, Šlechta, Miroslav   +2 more
openaire   +2 more sources

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

FEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Infrared emission lines of Mg II in B stars [PDF]

Symposium - International Astronomical Union, 1994
Recently, Chang et. al. (1992) and Carlsson, Rutten and Shchukina (1992) (CRS) demonstrated the non-LTE formation mechanism behind the 12 μm Mg I emission lines (6g–7h, 6h–7i) observed in the solar spectrum (Murcray et. al., 1981). CRS stress the generality of this mechanism showing that it is a natural consequence of the recombination flow from the ...
T. A. Aaron Sigut, J. B. Lester
openaire   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

New Symbiotic Stars from LAMOST DR10 Spectra and Multiband Photometry

The Astrophysical Journal
The Symbiotic star (SySt) is a long-period interacting binary system, typically consisting of a white dwarf (WD) and a red giant surrounded by a nebula. These systems are natural astrophysical laboratories for investigating binary star evolution. In this
Jing Chen, Liang Wang, Yin-Bi Li, Xiao-Xiao Ma, A-Li Luo, Zi-Chong Zhang, Ming-Yi Ding, Kai Zhang   +7 more
doaj   +1 more source